Introduction: Severe anemia is a major cause of morbidity and mortality in children. An epidemiological analysis would make it possible to estimate the related measures in order to fight effectively against their causes.Methods: The present retrospective descriptive study focuses on severe anemia in children under five years from January to December 2019. Sickle cell patients and children suffering from neoplasia were excluded from this study. All admissions from January to December 2019 and deaths, which met the selection criteria were listed.Results: Out of a total of 2,050 hospitalized children, 413 were admitted for severe anemia (20.1%), and 15.7% of deaths, i.e., a specific mortality of 31.6 p. 1000. Regarding the cause of severe anemia, malaria remains predominant in both sexes with 61.1% / 188 girls, respectively; and 52.9% / 225 boys. The study notes that anemia is much more common in the 2 – 5 years age group - 47.2%. At 88% of these children the outcome was favorable in their sex, also when the child lived in downtown Kabinda, ie 89.1%; also for the 2 - 5 year bracket, i.e. 90.3%.Conclusion: The implementation of the policy of free antimalarial drugs, the use of mosquito nets and awareness raising on basic hygiene measures must be effective. Strengthening these measures at the onset of the rainy seasons would prevent outbreaks of anemia.