Ngoc Hoi Nguyen1, Quang-Trung Nguyen2, Deepak T.A.3, Suchindra Suchindra4, and Avinash Tejasvi5
1 Institute of Chemical Technology, Academy of Science and Technology, Ho Chi Minh City, Vietn, Vietnam
2 Center for Research and Technology Transfer, Academy of Science and Technology, 18 HoangQuocViet, CauGiay, HaNoi, Vietn, Vietnam
3 Department of Oral Medicine and Radiology, V.S Dental College and Hospital, Bangalore, India
4 Department of Engineering, National Institute of Mental Health and Neurosciences, Bangalore, , Ind, India
5 Department of Oral Medicine and Radiology, Kameneni Institute of Dental Science, Narketpally, India
Original language: English
Copyright © 2024 ISSR Journals. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
DNA sequence DNA Sequencing is the first step in establishing phylogenetic trees, protein structure prediction, diagnosis of cancer, discovery of drugs and hence its importance cannot be underestimated. DNA sequencing finds its use in the diagnosis of oral squamous cell carcinoma (OSCC). Oral Cancer is the most common occurring malignancies in the world, especially in India where the prevalence for smoking, Areca nut chewing coupled with a lifestyle that encourages these two activities as fashion are left many people diagnosed with OSCC. Patients with this OSCC are more likely unaware of its side effects and over time might suffer from facial deformity. The importance to understanding the symptoms, prevention and treatment of oral cancer is very much essential today. In this paper, we looked at over 2000 odd papers published and look at the correlation between the next Generation DNA sequencing algorithms (NGS) play an important role in diagnosis of OSCC. This is a further study on some of the papers which have highlighted NGS role in OSCC Diagnosis. We did like to see a comprehensive review on the papers published so far. In the discussion, we will see frequently mutated genes in the OSCC, recent discoveries and OSCC treatment based on the findings.
Author Keywords: Sequence, phylogenetic Tree, Carcinoma, Gene.
