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International Journal of Innovation and Applied Studies
ISSN: 2028-9324     CODEN: IJIABO     OCLC Number: 828807274     ZDB-ID: 2703985-7
 
 
Sunday 27 September 2020

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Most effective preventive measure, key to reducing perinatal hepatitis-B virus, a global health strategy: Systematic review


Volume 29, Issue 2, May 2020, Pages 160–167

 Most effective preventive measure, key to reducing perinatal hepatitis-B virus, a global health strategy: Systematic review

Clement Kwabena Apaw1

1 School of Public Health, Southern Medical University, Guangzhou, China

Original language: English

Received 21 November 2019

Copyright © 2020 ISSR Journals. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract


Background: over 240 million of people are chronic hepatitis B carriers globally, acquired basically through vertical transmission. The infection is proportionally represented in all continent across the global. Purpose: The aim of this study is to systematically review articles to identify the most effective preventive measure to curb perinatal transmission of hepatitis B. Methods: A systematic search was done in PubMed and Science Direct for review and research articles with keywords used in this review. The research was restricted to January 2016 to December 2019 for open access review and research articles. I also searched for bibliographies for original research and studies Principal Results: Perinatal transmission hepatitis B is the main cause of chronic hepatitis B. Interventions like routine vaccination Hepatitis B virus (HBV) vaccine, combination of HBV vaccine and Hepatitis B Immunoglobulin, Antiviral therapy, and route of delivery (cesarean section and vaginal) has significantly influence in transmission of Hepatitis B to newborns. The combined interventions enumerated in World Health Organization (WHO) Health Strategy for curbing viral hepatitis is the ideal way to eliminate the disease by 2030 Major Conclusion: Identified preventive measure for curbing the spread of mother-to child transmission of Hepatitis B, singly not efficacious enough to eliminate the infection. Challenges identified in each implementation is solved with combination of two or more strategies put together. This is in agreement with WHO global health strategy 2030, for preventing viral hepatitis. More so, there is the need to identify the most effective preventive measure using meta-analysis.

Author Keywords: Perinatal transmission, Hepatitis B, Global Health Strategy, Mother-to-Child-Transmission, Preventive Measure.


How to Cite this Article


Clement Kwabena Apaw, “Most effective preventive measure, key to reducing perinatal hepatitis-B virus, a global health strategy: Systematic review,” International Journal of Innovation and Applied Studies, vol. 29, no. 2, pp. 160–167, May 2020.