International Journal of Innovation and Applied Studies
ISSN: 2028-9324     CODEN: IJIABO     OCLC Number: 828807274     ZDB-ID: 2703985-7
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Prevention of Mother to Child Transmission of Zika Virus and Associated Teratogenic Effects

Volume 29, Issue 3, June 2020, Pages 428–435

 Prevention of Mother to Child Transmission of Zika Virus and Associated Teratogenic Effects

Ruthie Sophie Mnyanga1

1 School of Public Health, Southern Medical University (SMU), Guangzhou, China

Original language: English

Received 5 February 2020

Copyright © 2020 ISSR Journals. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Background: Zika virus (ZIKV), a mosquito-borne flavivirus the same vector that causes Dengue and Chikungunya. ZIKV originated from Uganda and was first discovered in monkeys at Zika forest in 1947. Historically, ZIKV causes mild and self-limiting symptoms which can be observed in only 20folds of infected individuals. Recently, in 2015, ZIKV imaged in Brazil and has been linked to serious neurological complications including microcephaly. In 2016, the World Health Organization declared this fact as “Public Health Emergency” Objective: Review on possible mother to child transmission of ZIKV in utero and its related teratogenic effect. Method: Studies both in human and animal models revealed a relationship between ZIKV infection in pregnancy and neurological effects such as microcephaly in fetus and neonates. Result: ZIKV has been linked with microcephaly especially when symptoms emerged in a pregnant woman during first and early second trimester. Conclusion: Although there is a linkage between ZIKV and neurological effects such as microcephaly, most people still doubting as to whether the emerging problem of microcephaly is related to ZIKV infections which is known to present with mild and self-limiting symptoms.

Author Keywords: Zika virus, microcephaly, aedes mosquito, congenital abnormalities, vertical transmission.

How to Cite this Article

Ruthie Sophie Mnyanga, “Prevention of Mother to Child Transmission of Zika Virus and Associated Teratogenic Effects,” International Journal of Innovation and Applied Studies, vol. 29, no. 3, pp. 428–435, June 2020.