Volume 4, Issue 3, November 2013, Pages 512–523
Ghose Bishwajit1, Marce - Amara Kpoghomou2, Hasanbek Shamsitdinov3, Arun Kumar Mondal4, and Sudeb Sarker5
1 School of public health, Department of Nutrition and Food Hygiene, Tongji Medical College, Wuhan, Hubei, China
2 Department of Epidemiology and Biostatistics, Tongji Medical College, Wuhan, Hubei, China
3 Department of Pharmacology, Tongji Medical College, Wuhan, Hubei, China
4 Institute of Nutrition and Food Science, University of Dhaka, Dhaka, Bangladesh
5 Department of Biochemistry and Molecular Biology, University of Dhaka, Dhaka, Bangladesh
Original language: English
Copyright © 2013 ISSR Journals. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Cholesterol is an extremely important biological molecule involved in a multitude of biological processes regarded as vital for our survival. Yet, the function that has attracted more attention is its contribution to the development of atherosclerosis, a chronic inflammatory disease of blood vessels, which constitutes an underlying cause of coronary heart disease. Atherosclerosis is the principal cause of myocardial and cerebral infarction and remains the chief cause of death across many parts of the globe. Shockingly, despite its extreme physiological importance, cholesterol remains the most controversial nutrient ever. Misconception continues to exist not only among the people lacking knowledge in nutrition, but also among many nutrition researchers. The misconceptions surrounding cholesterol have been so pronounced and persistent that its beneficial effects are hardly heard of. Pharmaceutical companies are using this mass (cholesterolphobia) to flourish their business. However, recent studies demonstrate that cholesterol plays a minor role in cardiovascular disease. The objectives of this article are twofold. Firstly we review research articles to analyze the existing ideas regarding the link between heart diseases and cholesterol. Then we provide an up-to-date information about some health impacts of cholesterol and highlight the effects of anti-cholesterol drugs based on the researches performed to date.
Author Keywords: Cholesterol, Cardiovascular disease, Atherosclerosis, Inflammation, Anti-cholesterol drugs.
Ghose Bishwajit1, Marce - Amara Kpoghomou2, Hasanbek Shamsitdinov3, Arun Kumar Mondal4, and Sudeb Sarker5
1 School of public health, Department of Nutrition and Food Hygiene, Tongji Medical College, Wuhan, Hubei, China
2 Department of Epidemiology and Biostatistics, Tongji Medical College, Wuhan, Hubei, China
3 Department of Pharmacology, Tongji Medical College, Wuhan, Hubei, China
4 Institute of Nutrition and Food Science, University of Dhaka, Dhaka, Bangladesh
5 Department of Biochemistry and Molecular Biology, University of Dhaka, Dhaka, Bangladesh
Original language: English
Copyright © 2013 ISSR Journals. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Cholesterol is an extremely important biological molecule involved in a multitude of biological processes regarded as vital for our survival. Yet, the function that has attracted more attention is its contribution to the development of atherosclerosis, a chronic inflammatory disease of blood vessels, which constitutes an underlying cause of coronary heart disease. Atherosclerosis is the principal cause of myocardial and cerebral infarction and remains the chief cause of death across many parts of the globe. Shockingly, despite its extreme physiological importance, cholesterol remains the most controversial nutrient ever. Misconception continues to exist not only among the people lacking knowledge in nutrition, but also among many nutrition researchers. The misconceptions surrounding cholesterol have been so pronounced and persistent that its beneficial effects are hardly heard of. Pharmaceutical companies are using this mass (cholesterolphobia) to flourish their business. However, recent studies demonstrate that cholesterol plays a minor role in cardiovascular disease. The objectives of this article are twofold. Firstly we review research articles to analyze the existing ideas regarding the link between heart diseases and cholesterol. Then we provide an up-to-date information about some health impacts of cholesterol and highlight the effects of anti-cholesterol drugs based on the researches performed to date.
Author Keywords: Cholesterol, Cardiovascular disease, Atherosclerosis, Inflammation, Anti-cholesterol drugs.
How to Cite this Article
Ghose Bishwajit, Marce - Amara Kpoghomou, Hasanbek Shamsitdinov, Arun Kumar Mondal, and Sudeb Sarker, “Insights on cholesterol nutrition: shift to a new paradigm for better cardiovascular health,” International Journal of Innovation and Applied Studies, vol. 4, no. 3, pp. 512–523, November 2013.
