[ Activités antioxydantes des polyphenols extraits de plantes médicinales de la pharmacopée traditionnelle d'Algérie ]
Volume 9, Issue 1, November 2014, Pages 167–172
Boulanouar Bakchiche1 and Abdelaziz Gherib2
1 Département de Technologie, Université de Laghouat, Algérie
2 Département des Sciences, Université de Laghouat, Algérie
Original language: French
Copyright © 2014 ISSR Journals. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Oxidative stress is responsible for several diseases. This phenomenal has moved researchers into action in looking for new remedies «antioxidants». In this context, the study of the antioxidant activity of hydro-ethanolic extracts of eight (08) plants used in Algerian pharmacopoeia has been performed. These plants are from Laghouat region ((Atlas Sahara). The extracts from these eight plants were obtained by ultrasound assisted extraction. The quantitative estimation of flavonoids, flavanones and total phenols by the spectophotometric method showed that the eight extracts contain these compounds. The evaluation of antioxidant capacity by the method of free radical scavenging test showed that all of the extracts have a very good reductive activity, especially for Arbutus undo extract which presented a percentage of inhibition equal to 90% with an EC50 estimated to 0.006 mg/ml. On the other hand, the FRAP test revealed that the Zizyphus lotus extract has the best reducing power than those of the other extracts, but it remains relatively low compared to the ascorbic acid used as positive control.
Author Keywords: Medicinal plants, flavonoids, flavanones, total phenols, antioxidant activity.
Volume 9, Issue 1, November 2014, Pages 167–172
Boulanouar Bakchiche1 and Abdelaziz Gherib2
1 Département de Technologie, Université de Laghouat, Algérie
2 Département des Sciences, Université de Laghouat, Algérie
Original language: French
Copyright © 2014 ISSR Journals. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Oxidative stress is responsible for several diseases. This phenomenal has moved researchers into action in looking for new remedies «antioxidants». In this context, the study of the antioxidant activity of hydro-ethanolic extracts of eight (08) plants used in Algerian pharmacopoeia has been performed. These plants are from Laghouat region ((Atlas Sahara). The extracts from these eight plants were obtained by ultrasound assisted extraction. The quantitative estimation of flavonoids, flavanones and total phenols by the spectophotometric method showed that the eight extracts contain these compounds. The evaluation of antioxidant capacity by the method of free radical scavenging test showed that all of the extracts have a very good reductive activity, especially for Arbutus undo extract which presented a percentage of inhibition equal to 90% with an EC50 estimated to 0.006 mg/ml. On the other hand, the FRAP test revealed that the Zizyphus lotus extract has the best reducing power than those of the other extracts, but it remains relatively low compared to the ascorbic acid used as positive control.
Author Keywords: Medicinal plants, flavonoids, flavanones, total phenols, antioxidant activity.
Abstract: (french)
Le stress oxydant, cause de plusieurs maladies, suscite la recherche de nouveaux remèdes antioxydants. Dans cette optique, l'étude de l'activité antioxydante des extraits hydro-éthanoliques de huit (08) plantes utilisées dans la pharmacopée algérienne a été réalisée. Ces plantes sont issues de la région de Laghouat (Atlas Saharien). Les extraits des huit plantes sont obtenus par la sonication. L'estimation quantitative des flavonoïdes, des flavanones et des phénols totaux par la méthode spectrophotométrique a montré que ces huit extraits contiennent ces composés. L'évaluation du pouvoir anti-oxydant par la méthode du piégeage des radicaux libres a montré que les extraits étudiés ont tous une très bonne activité réductrice, surtout pour l'extrait d'Arbutus unedo ayant présenté un pourcentage d'inhibition égale à 90% avec une EC50 égale à 0,003 mg/ml. D'autre part, le test de FRAP a révélé que l'extrait Zizyphus lotus a le meilleur pouvoir réducteur par rapport ceux des autres extraits, mais qui reste, toutefois, relativement faible par rapport à celui de l'acide ascorbique utilisé comme contrôle positif.
Author Keywords: Plantes médicinales, flavonoïdes, flavanones, phénols totaux, activité anti-oxydante.
How to Cite this Article
Boulanouar Bakchiche and Abdelaziz Gherib, “Antioxidant activities of polyphenol extracts from medicinal plants in Algerian traditional pharmacopoeia,” International Journal of Innovation and Applied Studies, vol. 9, no. 1, pp. 167–172, November 2014.
