[ Effets d’une consommation modérée d’alcool sur la progéniture de la ratte (Wistar) ]
Volume 24, Issue 4, November 2018, Pages 1690–1700
Prisca Joëlle Djoman DOUBRAN1, Koffi Mathias YAO2, Niemtiah OUATTARA3, Antoine Némé TAKO4, and Bialli SERY5
1 Laboratoire de Neurosciences. Université Félix HOUPHOUET-BOIGNY, UFR Biosciences, 22 BP 582 Abidjan 22 , Côte d’Ivoire
2 Laboratoire de Neurosciences. Université Félix HOUPHOUET-BOIGNY, UFR Biosciences, 22 BP 582 Abidjan 22 , Côte d’Ivoire
3 Laboratoire de Neurosciences. Université Félix HOUPHOUET-BOIGNY, UFR Biosciences, 22 BP 582 Abidjan 22 , Côte d’Ivoire
4 Laboratoire de Neurosciences. Université Félix HOUPHOUET-BOIGNY, UFR Biosciences, 22 BP 582 Abidjan 22 , Côte d’Ivoire
5 Laboratoire de Neurosciences. Université Félix HOUPHOUET-BOIGNY, UFR Biosciences, 22 BP 582 Abidjan 22 , Côte d’Ivoire
Original language: French
Copyright © 2018 ISSR Journals. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
The objective of this study was to find the daily dose that could be safely consumed during the gestation period. Moderate doses of alcohol were administered to rats during gestation and the effects on the memory of progeny were assessed. The data indicate that from 0.3 gram per liter, any dose of alcohol becomes potentially harmful to the health of a fetus. Below this dose (0.1 grams per liter), even if the results obtained are not different from those of the controls, it is necessary to remain cautious since this study appreciates only one aspect on the memory. Indeed, there may be abnormalities on other functions with a daily consumption of 0.1grams per liter. It is therefore important to stress that the most cautious recommendation is abstinence throughout pregnancy because the dose limit Remains unknown.
Author Keywords: Alcohol consumption, pregnancy, progeny, memory.
Volume 24, Issue 4, November 2018, Pages 1690–1700
Prisca Joëlle Djoman DOUBRAN1, Koffi Mathias YAO2, Niemtiah OUATTARA3, Antoine Némé TAKO4, and Bialli SERY5
1 Laboratoire de Neurosciences. Université Félix HOUPHOUET-BOIGNY, UFR Biosciences, 22 BP 582 Abidjan 22 , Côte d’Ivoire
2 Laboratoire de Neurosciences. Université Félix HOUPHOUET-BOIGNY, UFR Biosciences, 22 BP 582 Abidjan 22 , Côte d’Ivoire
3 Laboratoire de Neurosciences. Université Félix HOUPHOUET-BOIGNY, UFR Biosciences, 22 BP 582 Abidjan 22 , Côte d’Ivoire
4 Laboratoire de Neurosciences. Université Félix HOUPHOUET-BOIGNY, UFR Biosciences, 22 BP 582 Abidjan 22 , Côte d’Ivoire
5 Laboratoire de Neurosciences. Université Félix HOUPHOUET-BOIGNY, UFR Biosciences, 22 BP 582 Abidjan 22 , Côte d’Ivoire
Original language: French
Copyright © 2018 ISSR Journals. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
The objective of this study was to find the daily dose that could be safely consumed during the gestation period. Moderate doses of alcohol were administered to rats during gestation and the effects on the memory of progeny were assessed. The data indicate that from 0.3 gram per liter, any dose of alcohol becomes potentially harmful to the health of a fetus. Below this dose (0.1 grams per liter), even if the results obtained are not different from those of the controls, it is necessary to remain cautious since this study appreciates only one aspect on the memory. Indeed, there may be abnormalities on other functions with a daily consumption of 0.1grams per liter. It is therefore important to stress that the most cautious recommendation is abstinence throughout pregnancy because the dose limit Remains unknown.
Author Keywords: Alcohol consumption, pregnancy, progeny, memory.
Abstract: (french)
L’objectif de cette étude a été de rechercher la dose quotidienne qui pourrait être consommée sans danger pendant la période de gestation. Des doses modérées d’alcool ont été administrées à des rates pendant la gestation et les effets sur la mémoire de la progéniture ont été évalués. Les données permettent d’affirmer qu’à partir de 0,3 gramme par litre, toute dose d’alcool devient potentiellement dangereuse pour la santé d’un fœtus. En dessous de cette dose (0,1gramme par litre), même si les résultats obtenus ne sont pas différents de ceux des témoins, il faut rester prudent puisque cette étude n’apprécie qu’un aspect sur la mémoire. En effet, il pourrait exister des anomalies sur d’autres fonctions avec une consommation quotidienne de 0,1 gramme par litre. Il reste donc important de souligner que la recommandation la plus prudente reste l’abstinence pendant toute la grossesse car la dose limite reste inconnue.
Author Keywords: Consommation d’alcool, gestation, progéniture, mémoire.
How to Cite this Article
Prisca Joëlle Djoman DOUBRAN, Koffi Mathias YAO, Niemtiah OUATTARA, Antoine Némé TAKO, and Bialli SERY, “Effects of moderate alcohol consumption on the Wistar rate progeny,” International Journal of Innovation and Applied Studies, vol. 24, no. 4, pp. 1690–1700, November 2018.
