[ Modalités de prescription ambulatoire des médicaments psychotropes au centre hospitalier psychiatrique national de Thiaroye à Dakar (Sénégal) ]
Volume 41, Issue 4, February 2024, Pages 1032–1043
DIAGNE Ibra1, DIEYE Maimouna2, WADE Racky3, PETIT Véronique4, NDIAYE-NDONGO Ndèye Dialé5, and SYLLA Aida6
1 Psychiatre au Centre des opérations d’urgence sanitaire du ministère de la santé et de l’action sociale du Senegal, Dakar, Senegal
2 Psychiatre et addictologue au centre Hospitalier Psychiatrique National de Thiaroye, Dakar, Senegal
3 Psychiatre et chercheur en anatomie, laboratoire d’anatomie et d’Organogénèse, Université Cheikh Anta Diop, Dakar, Senegal
4 Chercheur à l’IRD, Professeure des Universités, démographe, UMR 196 CEPED Université de Paris, Paris, France
5 Professeur en psychiatrie, Université Cheikh Anta Diop de Dakar, Centre Hospitalier National Universitaire de Fann, Dakar, Senegal
6 Professeur en psychiatrie, Université Cheikh Anta Diop de Dakar, Centre Hospitalier National Universitaire de Fann, Dakar, Senegal
Original language: French
Copyright © 2024 ISSR Journals. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
The objectives of this study were to describe and analyze the modalities of prescription of psychotropic drugs in patients followed in ambulatory psychiatry. The study was cross-sectional, descriptive, and analytical on the prescription of psychotropic drugs in 205 patients followed at the outpatient clinic of the National Psychiatric Hospital of Thiaroye in Dakar, for a period of three months (from February 1 to April 30, 2019). The average age was 34.5 years, 64.9% of patients were without occupation and 15.6% had a history of hospitalization. The disorder had lasted between 1 - 10 years for 59.1% of patients. The most frequent diagnosis was schizophrenia (33.7%) followed by mood disorders (18.1%) and epilepsy (18.0%). The average number of medications per patient was 2.77 and monotherapy was exceptional (0.06% of patients). Antipsychotics were the most prescribed drugs (76.1%), followed by anxiolytics (31.7%), thymoregulators (27.3%), and antidepressants (23.4%). A synthetic antiparkinsonian was found in 51.2% of cases and delayed neuroleptics were prescribed in 13.7% of patients. Classic antipsychotics were prescribed in 50.4% of schizophrenic patients and second-generation antipsychotics in 33.3%. Second-generation antidepressants (serotonin reuptake inhibitors and serotonin-norepinephrine reuptake inhibitors) were prescribed exclusively for depressive disorders and anxiety disorders, unlike tricyclics. One-third of bipolar patients (37.5%) received a combination of a thymoregulator and an antipsychotic. Contrary to antipsychotics, which are still dominated by the classics, we note a trend toward the prescription of new antidepressants. However, some prescriptions did not comply with international recommendations. It is important to set up national protocols, based on current scientific evidence but also on the socio-economic context of the country to optimize the quality of psychotropic drug prescriptions.
Author Keywords: Psychotropic drugs, prescription, psychiatry, Thiaroye, Senegal.
Volume 41, Issue 4, February 2024, Pages 1032–1043
DIAGNE Ibra1, DIEYE Maimouna2, WADE Racky3, PETIT Véronique4, NDIAYE-NDONGO Ndèye Dialé5, and SYLLA Aida6
1 Psychiatre au Centre des opérations d’urgence sanitaire du ministère de la santé et de l’action sociale du Senegal, Dakar, Senegal
2 Psychiatre et addictologue au centre Hospitalier Psychiatrique National de Thiaroye, Dakar, Senegal
3 Psychiatre et chercheur en anatomie, laboratoire d’anatomie et d’Organogénèse, Université Cheikh Anta Diop, Dakar, Senegal
4 Chercheur à l’IRD, Professeure des Universités, démographe, UMR 196 CEPED Université de Paris, Paris, France
5 Professeur en psychiatrie, Université Cheikh Anta Diop de Dakar, Centre Hospitalier National Universitaire de Fann, Dakar, Senegal
6 Professeur en psychiatrie, Université Cheikh Anta Diop de Dakar, Centre Hospitalier National Universitaire de Fann, Dakar, Senegal
Original language: French
Copyright © 2024 ISSR Journals. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
The objectives of this study were to describe and analyze the modalities of prescription of psychotropic drugs in patients followed in ambulatory psychiatry. The study was cross-sectional, descriptive, and analytical on the prescription of psychotropic drugs in 205 patients followed at the outpatient clinic of the National Psychiatric Hospital of Thiaroye in Dakar, for a period of three months (from February 1 to April 30, 2019). The average age was 34.5 years, 64.9% of patients were without occupation and 15.6% had a history of hospitalization. The disorder had lasted between 1 - 10 years for 59.1% of patients. The most frequent diagnosis was schizophrenia (33.7%) followed by mood disorders (18.1%) and epilepsy (18.0%). The average number of medications per patient was 2.77 and monotherapy was exceptional (0.06% of patients). Antipsychotics were the most prescribed drugs (76.1%), followed by anxiolytics (31.7%), thymoregulators (27.3%), and antidepressants (23.4%). A synthetic antiparkinsonian was found in 51.2% of cases and delayed neuroleptics were prescribed in 13.7% of patients. Classic antipsychotics were prescribed in 50.4% of schizophrenic patients and second-generation antipsychotics in 33.3%. Second-generation antidepressants (serotonin reuptake inhibitors and serotonin-norepinephrine reuptake inhibitors) were prescribed exclusively for depressive disorders and anxiety disorders, unlike tricyclics. One-third of bipolar patients (37.5%) received a combination of a thymoregulator and an antipsychotic. Contrary to antipsychotics, which are still dominated by the classics, we note a trend toward the prescription of new antidepressants. However, some prescriptions did not comply with international recommendations. It is important to set up national protocols, based on current scientific evidence but also on the socio-economic context of the country to optimize the quality of psychotropic drug prescriptions.
Author Keywords: Psychotropic drugs, prescription, psychiatry, Thiaroye, Senegal.
Abstract: (french)
Les objectifs de cette étude étaient de décrire et d’analyser les modalités de prescription des psychotropes chez les patients suivis en psychiatrie ambulatoire. L’étude était transversale, descriptive et analytique sur la prescription des psychotropes chez 205 patients suivis à la consultation externe de l’hôpital psychiatrique national de Thiaroye à Dakar, pendant une période de trois mois (du 1er février au 30 avril 2019). L’âge moyen était de 34,5 ans, 64,9% des patients étaient sans profession et 15,6% avaient des antécédents d’hospitalisation. Les troubles duraient depuis 1 à 10 ans pour 59,1 % des patients. Le diagnostic le plus fréquent était la schizophrénie (33,7 %), suivie des troubles de l’humeur (18,1 %) et de l’épilepsie (18,0 %). Le nombre moyen de médicaments par patient était de 2,77 et la monothérapie était exceptionnelle (0,06% des patients). Les antipsychotiques étaient les médicaments les plus prescrits (76,1%), suivis des anxiolytiques (31,7%), des thymorégulateurs (27,3%) et des antidépresseurs (23,4%). Un antiparkinsonien de synthèse a été retrouvé dans 51,2% des cas et des neuroleptiques retard ont été prescrits chez 13,7% des patients. Les antipsychotiques classiques ont été prescrits à 50,4% des patients schizophrènes et les antipsychotiques de seconde génération à 33,3%. Les antidépresseurs de deuxième génération (inhibiteurs de la recapture de la sérotonine et inhibiteurs de la recapture de la sérotonine et de la noradrénaline) ont été prescrits exclusivement pour les troubles dépressifs et les troubles anxieux, contrairement aux tricycliques. Un tiers des patients bipolaires (37,5%) ont reçu une combinaison d’un thymorégulateur et d’un antipsychotique. Contrairement aux antipsychotiques, toujours dominés par les classiques, on note une tendance à la prescription de nouveaux antidépresseurs. Cependant, certaines prescriptions ne sont pas conformes aux recommandations internationales. Il est important de mettre en place des protocoles nationaux, basés sur les preuves scientifiques actuelles mais aussi sur le contexte socio-économique du pays pour optimiser la qualité des prescriptions de psychotropes.
Author Keywords: Médicaments psychotropes, prescription, psychiatrie, Thiaroye, Sénégal.
How to Cite this Article
DIAGNE Ibra, DIEYE Maimouna, WADE Racky, PETIT Véronique, NDIAYE-NDONGO Ndèye Dialé, and SYLLA Aida, “Ambulatory prescription modalities of psychotropic drugs at Thiaroye National Psychiatric Hospital Center in Dakar (Senegal),” International Journal of Innovation and Applied Studies, vol. 41, no. 4, pp. 1032–1043, February 2024.
