This research aims to study the obstacles encountered by young Congolese graduates in setting up their businesses. Identifying these barriers provides useful knowledge to help young people succeed in their entrepreneurial activities and projects. To this end, we examine a sample of 588 young Congolese graduates of higher and university education located in the city of Kinshasa, in the Democratic Republic of Congo (DRC). A research approach made up of quantitative techniques, specifically the questionnaire survey, made it possible to collect the data necessary to understand the obstacles to business creation by young Congolese graduates. We opted for exploratory research. Three groups of major obstacles are mentioned in this research: the individual obstacles to business creation among young people, the obstacles related to the economic, institutional and regulatory, cultural, social and educational environment for the creation of a business companies and finally, the obstacles linked to the business creation project. The results of the study reveal that young people perceive difficult access to financing, difficult access to credit, lack of professional experience, absence or insufficient support and accompaniment, lack of personal funds, insufficient education and training programs, difficulties in preparing the business plan, lack of entrepreneurial culture, a policy of guidance and information, and skills and knowledge in entrepreneurship as the main obstacles to starting a business. This study ends with recommendations on how to improve youth entrepreneurship in the DRC.