Volume 13, Issue 3, November 2015, Pages 656–662
Tran Thi Minh Tam1, Nguyen Thi Huong Giang2, and Nguyen Thuy Huong3
1 Department of Biotechnology, Ho Chi Minh City University of Technology, Ho Chi Minh, Vietnam
2 Department of Biotechnology, Ho Chi Minh City University of Technology, Ho Chi Minh, Vietnam
3 Department of Biotechnology, Ho Chi Minh City University of Technology, Ho Chi Minh, Vietnam
Original language: English
Copyright © 2015 ISSR Journals. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
L-Lysine fermentation by Corynebacterium glutamicum obtained productivity improvements from D-glucose. Immobile Corynebacterium glutamicum on carrier brings many significant advantages for lysine production such as high reused ability, saving seed preparation stage and high adaptation ability of immobile cells to the fermentation environment. Simultaneously, immobile cells have a long phase for lysine excretion. L-Lysine fermentation kinetics by immobile cells is studied in the basic way to solve problems related to cell physiology. Thereby, optimization techniques are carried out more easily to determine the most suitable nutrient medium as well as fermentation conditions and result in obtaining highest yield L-Lysine. L-lysine concentration was improved to the level of 28.767
Author Keywords: Batch kinitics, L-Lysine, C. glutamicum, alginate, bacterial cellulose, reusing finished immobile cells.
Tran Thi Minh Tam1, Nguyen Thi Huong Giang2, and Nguyen Thuy Huong3
1 Department of Biotechnology, Ho Chi Minh City University of Technology, Ho Chi Minh, Vietnam
2 Department of Biotechnology, Ho Chi Minh City University of Technology, Ho Chi Minh, Vietnam
3 Department of Biotechnology, Ho Chi Minh City University of Technology, Ho Chi Minh, Vietnam
Original language: English
Copyright © 2015 ISSR Journals. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
L-Lysine fermentation by Corynebacterium glutamicum obtained productivity improvements from D-glucose. Immobile Corynebacterium glutamicum on carrier brings many significant advantages for lysine production such as high reused ability, saving seed preparation stage and high adaptation ability of immobile cells to the fermentation environment. Simultaneously, immobile cells have a long phase for lysine excretion. L-Lysine fermentation kinetics by immobile cells is studied in the basic way to solve problems related to cell physiology. Thereby, optimization techniques are carried out more easily to determine the most suitable nutrient medium as well as fermentation conditions and result in obtaining highest yield L-Lysine. L-lysine concentration was improved to the level of 28.767
Author Keywords: Batch kinitics, L-Lysine, C. glutamicum, alginate, bacterial cellulose, reusing finished immobile cells.
How to Cite this Article
Tran Thi Minh Tam, Nguyen Thi Huong Giang, and Nguyen Thuy Huong, “Study on Batch Fermentation Kinetics of L-Lysine by C. glutamicum immobilized on complex carriers of Alginate and Bacterial Cellulose and investigate its reused ability for further fermentative cycle,” International Journal of Innovation and Applied Studies, vol. 13, no. 3, pp. 656–662, November 2015.
