[ Sensibilité des Salmonelles Typhimurium vis-à-vis des extraits totaux de Costus afer in vitro ]
Volume 34, Issue 2, November 2021, Pages 145–150
Tshipele Ondas Arnold1, Pitu Mbabu Hugo2, Pungi Phambu Sandrine3, Futi Yi Nkimi Sambu4, Mayina Phuati Cloery5, and Nlandu Khonde Alphonse6
1 Institut Supérieur de Techniques Médicales de Tshela (ISTM, TSHELA), RD Congo
2 Institut Supérieur de Techniques Médicales de Tshela (ISTM, TSHELA), RD Congo
3 Institut Supérieur d’Études Agronomiques de Tshela (ISEA, TSHELA), RD Congo
4 Institut Supérieur de Techniques Médicales de Tshela (ISTM, TSHELA), RD Congo
5 Institut Supérieur de Techniques Médicales de Tshela (ISTM, TSHELA), RD Congo
6 Institut Supérieur de Techniques Médicales de Tshela (ISTM, TSHELA), RD Congo
Original language: French
Copyright © 2021 ISSR Journals. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Typhoid fever remains, today, a major public health problem worldwide with a universal estimate of 12 to 33 million annual cases. It is caused by a strictly human species, Salmonella typhi, discovered since 1880 by Eberth.Typhoid fever has long been the cause of human disasters across the world: in the 17th century, for example, 600 people died from this disease in James Towen in Virginia (USA).Indeed, the defective hygienic conditions of our immediate environment place S. typhi at the first rank of the main causes of food poisoning, typhoid fever is also the main disease of « dirty hands ».Formerly effective, most antibiotics have shown their limits: which leads researchers to turn to plants (traditional medicine) to assess their sensitivity to salmonella typhi.Costus afer has been used in certain regions as a medicinal decoction against hemorrhoids and liver diseases for a long time, we thought to test in vitro its activity against S. typhi.Of this research, 67% of the typhus strains tested were sensitive below 3%, the strains became resistant: 33% for greatly reduced concentrations.
Author Keywords: Sensitivity, total extracts, costus afer, Salmonella.
Volume 34, Issue 2, November 2021, Pages 145–150
Tshipele Ondas Arnold1, Pitu Mbabu Hugo2, Pungi Phambu Sandrine3, Futi Yi Nkimi Sambu4, Mayina Phuati Cloery5, and Nlandu Khonde Alphonse6
1 Institut Supérieur de Techniques Médicales de Tshela (ISTM, TSHELA), RD Congo
2 Institut Supérieur de Techniques Médicales de Tshela (ISTM, TSHELA), RD Congo
3 Institut Supérieur d’Études Agronomiques de Tshela (ISEA, TSHELA), RD Congo
4 Institut Supérieur de Techniques Médicales de Tshela (ISTM, TSHELA), RD Congo
5 Institut Supérieur de Techniques Médicales de Tshela (ISTM, TSHELA), RD Congo
6 Institut Supérieur de Techniques Médicales de Tshela (ISTM, TSHELA), RD Congo
Original language: French
Copyright © 2021 ISSR Journals. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Typhoid fever remains, today, a major public health problem worldwide with a universal estimate of 12 to 33 million annual cases. It is caused by a strictly human species, Salmonella typhi, discovered since 1880 by Eberth.Typhoid fever has long been the cause of human disasters across the world: in the 17th century, for example, 600 people died from this disease in James Towen in Virginia (USA).Indeed, the defective hygienic conditions of our immediate environment place S. typhi at the first rank of the main causes of food poisoning, typhoid fever is also the main disease of « dirty hands ».Formerly effective, most antibiotics have shown their limits: which leads researchers to turn to plants (traditional medicine) to assess their sensitivity to salmonella typhi.Costus afer has been used in certain regions as a medicinal decoction against hemorrhoids and liver diseases for a long time, we thought to test in vitro its activity against S. typhi.Of this research, 67% of the typhus strains tested were sensitive below 3%, the strains became resistant: 33% for greatly reduced concentrations.
Author Keywords: Sensitivity, total extracts, costus afer, Salmonella.
Abstract: (french)
La fièvre typhoïde demeure encore, de nos jours, un grand problème de santé publique dans le monde entier avec une estimation universelle de 12 à 33 millions des cas annuels. Elle est causé par une espèce strictement humaine, la Salmonella typhi découvert depuis 1880 par Eberth.Depuis longtemps, la fièvre typhoïde cause des désastres humains à travers le monde: au XVIIe siècle par exemple, 600 personnes sont mortes de cette affection à James Towen en virginie (USA).En effet, les conditions hygiéniques défectueuses de notre environnement immédiat placent le S.typhi au premier rang des causes principales des toxi – infections alimentaires, la fièvre typhoïde constitue d’ailleurs la principale maladie des « mains sales ».Jadis efficaces, la plupart d’antibiotiques ont montré leur limites: ce qui pousse les chercheurs à se tourner vers les plantes (médecine traditionnelle) pour évaluer leur sensibilité vis-à-vis de salmonella typhi.Le Costus afer est utilisé dans certaine région comme décoction médicinale contre les hémorroïdes et les affections hépatiques depuis longtemps, nous avons pensé tester in vitro son activité vis-à-vis de S.typhi.De ces recherches, 67% des souches typhiques testées furent sensibles en deçà de 3%, les souches devenaient résistantes: 33% pour des concentrations fortement diminuées.
Author Keywords: Sensibilité, extraits totaux, costus afer, Salmonella.
How to Cite this Article
Tshipele Ondas Arnold, Pitu Mbabu Hugo, Pungi Phambu Sandrine, Futi Yi Nkimi Sambu, Mayina Phuati Cloery, and Nlandu Khonde Alphonse, “Sensitivity of Salmonella Typhimurium to total extracts of Costus afer in vitro,” International Journal of Innovation and Applied Studies, vol. 34, no. 2, pp. 145–150, November 2021.
