Innovation, a subject of massive interest:
- is multiple and subject to overlapping descriptors: Closed, Open, Collaborative, Disruptive, Inclusive, Nested

"Innovation is not the idea, but what you do with it". Can ideation be engendered by artificial means? Can it come from bio-inspiration?
In this third review centered on innovation, open innovation, and now disruptive innovation, the authors have reviewed and re-contextualized various bio-inspired technologies ranking from pharmaceutical developments, medical treatments, software and hardware, energy, materials and natural polymers.
This after a refreshing introduction associated with 1- the skills of the "bio-inspired" business engineer, 2- the open innovation process path and discipline therewith and 3- the patent value of the pioneering, possibly disruptive inventions in the typical patent portfolio.
A knowledge flow pattern, from sharing, integration, search, generation, classification, dissemination, to application, is proposed to outline the necessary understanding of bio-inspiration to yield application of innovative value; still nurturing the proposed knowledge "life cycle".
The necessary creative confidence can be gained, reinforced by the bio-observation and inspiration; nonetheless a larger set of functions may need to take part to the innovation process with their own recognized and valued creative potential and phobia elimination.
When performed by enlarged teams comprising the engineer, scientist, IP strategist, business model expert, sales and marketing teams, accountant, executive and operating teams, the ATA