Nutrient contents and antioxidant capacity of four tomato varieties (UC82 b, Amiral F1, locale cotelette and locale cerise) were determined by spectrophotometric method. Among these varieties, Amiral F1 had the highest antioxidant capacity with an EC50 of 3.47 mg/mL and rate of total polyphenols (17.5 mg/100 g GAE). In addition, locale cotelette was richer in lycopene (2.9 mg per 100 g of fresh tomatoes) and vitamin C (35.4 mg/100 g of fresh tomatoes) than other tomato varieties. The highest calcium (31 mg per 100 g of fresh tomatoes), magnesium (21 mg per 100 g of fresh tomatoes) and potassium (333 mg per 100 g of fresh tomatoes) contents were also observed for this variety in particular. The results highlighted that UC82 b was the best source of iron (0.065 mg per 100g of fresh tomatoes), phosphorus (23 mg per 100 g of fresh tomatoes), manganese (0.086 mg per 100 g of fresh tomatoes) and zinc (0.11 mg per 100 g of fresh tomatoes). This work showed that the different varieties of tomatoes studied have high antioxidant capacity. Thus, they could be used to prevent oxidative stress.