E-commerce is distinguished from traditional commerce through the dematerialization of its activities due to the use of Information and Communication technologies over the Internet. This research examines issues related to the problems of dematerialization of e-commerce activities, as well as its omnipresence (ubiquity) manifested by the fact that the e-commerce website is accessible in almost all countries and depersonalization, which creates risks due, on the one hand, to the lack of the physical presence of the contractors and, on the other hand, to the use of the electronic medium to conclude the contract. The objective is to provide information on the applicability of virtual commerce practices in order to secure the professional environment of the e-commerce through the protection of general rules such as information provided by companies, practices unfair commercial terms, unfair contract clauses, online payment security, data protection and confidentiality, dispute resolution and remedies, and international electronic transactions.