This study was conducted to estimate the prevalence of Salmonella in food products of animal origin intended for human consumption, sold in the local market of the prefecture of Rabat. 631 samples were taken between July 2020 and December 2022. The isolation of Salmonella was carried out using the NMISO7965-1 (2017) method. All the Salmonella isolated were confirmed by the Maldi-Tof mass spectrometry method (Biotyper – Sirius IVD System). Of the 631 samples examined, Salmonella was isolated in 3.01% (19/631) of the samples. The prevalence of Salmonella by product is respectively 16.95% in red meat, 12.73% in poultry meat, 1.54% in fish products and 0.51% in dairy products. Salmonella was not isolated from eggs and from ready to eat food. Salmonella can be transmitted to human populations through the consumption of food contaminated with Salmonella, it is a worrying public health problem in Morocco.