This reflection focuses on the spatial and socio-economic factors that hinder the development of domestic air transport in Côte d’Ivoire. This research is carried out in a context where Ivorian authorities, after independence, undertook significant actions to promote the growth of domestic air transport in Côte d’Ivoire. These actions included the establishment of an institutional and regulatory framework, as well as the creation of an airline fleet, including Air Ivoire, for the service of the territory and the establishment of airports throughout the country. However, despite all these actions, the current situation shows that, more than half a century later, domestic air transport represents less than 10% of travel in Côte d’Ivoire. This study aims to analyze the spatial constraints to the development of domestic air transport in Côte d’Ivoire. The data used to achieve this objective come from documentary research, field observation, and surveys of domestic air transport stakeholders in Côte d’Ivoire. At the end of these investigations, the study reveals that the regression in the number of airports, the narrowness of the Ivorian territory, and the spatial disparities caused by the macrocephaly of the city of Abidjan are the spatial factors that hinder the development of domestic air transport.