In this study, atmospheric pressure glow discharge plasma was used to modify the surface properties of wool/polyamide fabric, the effect of air plasma treatment on the printing properties of wool/polyamide blend was also discussed. Three dyes were used namely acid dye, basic dye, and reactive dye. Different exposure time and discharge current of air plasma treatment were investigated to impart changes in wool/polyamide properties, such as whiteness, wettability, tensile strength, elongation, felting shrinkage, color intensity, and fastness properties. The surface characterization was performed using FTIR and SEM analysis. The plasma treatments enhance the colour strength of the wool/polyamide blend with acid, basic, and reactive dyestuffs as well as the fastness properties, and represent an approach to printing the blend with single dye.