Food security is a major challenge for developing countries. Non-Timber Forest Products (NTFPs) are a source of income for families, improving their living conditions. Tamarind is a NTFP used for many purposes, both for food and industrial purposes. However, it suffers from pest attacks. This study aimed to evaluate the post-harvest practices of tamarind fruits and the constraints related to its storage in the communes of Bobo-Dioulasso and Ouagadougou. A survey conducred in the form of a semi-structured interview toward 113 respondents in Bobo-Dioulasso and 138 in Ouagadougou. The participatory diagnosis showed that the majority of respondents in Bobo-Dioulasso (70.19%) and Ouagadougou (57.33%) considered insects to be the main cause of damage to the pods. We observe a preponderance of perforated beans (63.16%) in Ouagadougou, while in Bobo-Dioulasso the percentage was 29.85. After collecting the pods, 78.95% of the farmers in Ouagadougou dehull the pods immediately and then keep the pulp without further drying, in contrast to Bobo-Dioulasso (16.67%) where only a minority practice this. More than half of the interviewers sell tamarind to meet specific needs. As for control methods, the main ones are steaming of tamarind used by 72.92% of farmers in Ouagadougou, while in Bobo-Dioulasso only 25.64%. These results show that tamarind pods are highly exposed to insect attacks. It is therefore necessary to investigate the improvement of traditional control methods by including other natural alternatives in order to minimize losses and promote tamarind exploitation.