This paper presents the design and experimental study of a new electronic ESP32-based control device of an anti-mold enclosure for the conservation of luxury leather goods. The control specifications deal with temperature control inside the enclosure between 18 oC and 25 oC, while maintaining the internal humidity rate between 50% and 60%, for the sake of better conservation of leather products. The virtual schematic diagram of the device is developed with EasyEDA, then the virtual assembly diagram is realized using Fritzing. The complete experimental device is realized and well tested using several electronic modules, including: DHT22 sensor, ESP32 microcontroller, Peltier effect module and LCD display. In addition, an application program is developed using Arduino C++ and uploaded into ESP32. Finally, the testing results presented and discussed confirm the quality and originality of this novel device for digital control of leather product preservation enclosures.