In order to promote congolese plants with antihypertensive properties, two hypotensive (antihypertensive) extracts of Trema orientalis B. leaves were selected in order to know their flavonoid profiles. Therefore, these extracts were prepared and underwent bioguided fractionations until the isolation of the compounds on silica gel. These ethanolic and aqueous extracts presented similar characteristics (appearance, solubility in polar solvents, color of spots at UV 365 nm, frontal ratio). Five compounds were isolated from these extracts of Trema orientalis leaves. The analytical data of these compounds show a similarity of physical and chemical characteristics. These compounds presented in NMR1H the same basic structure of the flavonoid type, 5,7,4’-trihydroxyl-2,3-dihydroflavonol (Kaempferol) or 5,7,4’-trihydroxyl-2,3-dihydroisoflavonol of gross formula C15H12O6 and differ on their osidic part. Therefore, the definitive structural determination of these compounds must be confirmed by other more in-depth analyses. They will allow to valorize this plant by the production of phytoproducts rich in flavonoids antihypertensive and with oxidizing power.