The aim of this study is to determine the share of coccidiosis in the mortality of young guinea fowl (keets) on farms in northern Côte d’Ivoire. Thus, a study was carried out on 192 one-day-old guinea fowl, divided into two (2) batches. The control batch did not receive treatment. The experimental batch was treated with an anticoccidial. Then, the zootechnical parameters and the degree of infestation were measured in each of the batches. The control batch recorded EPG values ​​of 600; 7371.43 and 5442.86 respectively for age groups 0-21d; 22-48d and 49-90d. these values ​​are significantly and respectively 8.6 times; 81.7 times and 63.19 times higher (p < 0.001) than those of the experimental group for the same age groups. As for mortality, it is 75% in the Control batch, three times higher than that of the experimental batch. Also, keets subjected to anticoccidial treatment recorded the best growth performance. Coccidiosis is therefore one of the main causes of the high mortality observed in guinea fowl farms in northern Côte d’Ivoire. Thus, the prevention of coccidiosis could help improve the profitability of guinea fowl farms in Côte d’Ivoire. However, the use of biological solutions as an alternative to synthetic antibiotics would be an avenue to explore in order to prevent the solution to this problem from being the start of another problem, in particular that of the resistance of germs to antibiotics.