This study was conduct at the Centre de Recherche en Sciences Naturelles de Lwiro to evaluate the anthelmitic activity of aqueous and ethanolic extracts of Viscum congolensis and Galiniera coffeoides, two plants collected in Kahuzi-Biega National Park. The objective was to assess their activity against earthworms Alma emini. The aqueous extracts are efficacy than ethanolic extracts. Their concentrations varied between 2 and 0.2 mg/mL. These results were compared to positives control (Mebendazole, Albendazole and Decaris) and negative one (water). The detailed are necessary for the isolation, characterization and evaluation of the substances responsible of anthelmitic activity and the action mode of the substance identified.