Terminalia laxiflora is multipurpose tree in Sudan. But it has low germination percentage, which may affect its natural regeneration. There were evidence that the fruits have an inhibitory effect, so this study was carried out to determine which part of the fruit that affect germination and seedlings growth. Three parts of the fruit extraction were examine (Coat, Pulp and Wing) with tow concentration to each part (200 fruit/litre, 100 fruit/litre).the results showed that all extractions had no effect on germination percentage except fruit coat extract (200 fruit/litre), which reduced it significantly. The different extractions had no effect on root length and seem to elongate the shoot expect fruit pulp (200 fruit/litre), which no different from control. All extractions had no effect on first leave appearance, but they causing abnormal seedlings. The result suggest new treatments that could be applied on the fruit of this species like de winging or de pulping the fruit before sewing or soaking in acid or hot water after de winging, de pulping and de coating. These results can be of great value for the medicinal plant scientists and users to try T. laxiflora fruit extractions for controlling bacteria and fungi activities and it may be an addition benefit to the medicinal uses of this tree.