The current study was aimed to analyze the ill effects of chronic cigarette, marijuana and marijuana plus cigarette smoking on the reproductive health of addicted men. The study was carried out in district Dir, Khyber Pakhtunkhwa (Pakistan). Four groups were made. These groups were control, cigarette smokers, marijuana smokers and marijuana plus cigarette smokers. Each group included 15 participants. Their age range was 30 to 40 years. A questionnaire was filled and blood samples were analyzed for serum total testosterone level by using Bio-check (USA) kit. A significantly reduced testosterone level was found in cigarette smokers (Mean