Hepatitis B virus (HBV) and hepatitis C virus (HCV) both of them are established causes of post transfusion hepatitis which considered as the commonest causes of chronic liver disease in the several regions of the world. To estimate the prevalence of HBV and HCV among blood donors in Missan governorate. A cross sectional study was conducted in Missan governorate and the data collected from records of blood bank during 2010-2012. A total of 36620 blood donors were selected. The prevalence of hepatitis B virus was 0.12% (44) while the hepatitis C virus prevalence was 0.09% (34), both of HBV and HCV were most common in male and in urban area. A decline in trend of hepatitis B and C virus during 2010-2012 was shown in the study. We concluded that the prevalence of HBV and BCV was lower than other studies that were conducted in Iraq. There is increasing in public awareness about hepatitis infection.
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