We investigated histochemically the expression of glycans in the mouse ventral prostate of the normal, castrated, castrated mice injected with testosterone (T) and castrated mice injected with dihydrotestosterone (DHT). The avidin-biotin-peroxidase complex technique was used with eight biotinylated lectins, on paraffin sections. Remarkably, contrarily to T, the DHT found to restore all the glycans in epithelial cells of ventral prostate. The histophysiological significance of the activation synthesis of glycoconjugates in mouse ventral prostate by DHT is discussed in the light of the other studies obtained mainly in humans.