New γ-lactam derivatives are synthesized with good yields on a mineral support in "dry" medium and under microwave irradiations in a domestic furnace. The structures of the various products are established using 1HNMR, 13CNMR and IR spectroscopy.
In this work, we report an efficient protocol containing the technique of microwave oven and its comparison with the conventional method (refluxing) for the synthesis of new derivatives pyridazinones namely 4-(p-alkylbenzylidene)pyridazin-3(2H)-ones. These are obtained by condensation of α-arylidene-γ-butyrolactones precursors and hydrazines in the presence of p-toluene sulfonic acid (PTSA). The structures of these new compounds were identified by spectral methods (1H, 13C NMR and IR).