The main objective of this synthesis is the state of knowledge, potential, inadequacies and interest of assembling two bioindicators, specifically zooplankton organisms and aquatic macroinvertebrates. The analysis of published articles, master theses, doctoral theses, technical information documents, manuals and identification guides and other documents relating to the study of the two groups of organisms in the tropical region was made. According to this analysis, aquatic zooplankton and macroinvertebrate organisms are extremely diverse and have potential sentinel species (pollu-sensitive and pollu-tolerant). These two groups of biondicators, by their diversity of taxonomic and functional forms, their variable life span, their wide distribution in running water and their different trophic positions, are complementary and thus constitute excellent tools for assessing the state of Health of hydrosystems. Their association would make it possible to account for the perfect state of health on all the sectors of the aquatic ecosystems. This article gives an overview of what is known about commonly used bioindicators, reveals some shortcomings of the work carried out and finally proposes guidelines for future studies.