The study sought to explore the prevalence and societal influence on drug and substance abuse among secondary school going teenagers in the Shiselweni region of Swaziland. Exploratory sequential mixed method research design was employed. Focus group discussions with 35 learners who were drug and substance abusers were selected using snowball sampling. In-depth interviews with four principals of the selected schools were done to generate qualitative data and these were selected using the criterion purposive sampling method. The generated qualitative data were analysed using thematic analysis and were used to form items of a questionnaire given to 200 randomly selected students for quantitative data. Quantitative data were analysed using descriptive statistics, frequencies, mean and standard deviation. The study revealed that drug and substance abuse was prevalent among teenage learners and the society was encouraging drugs and substances abuse. A programme to deal with abuse problems was recommended.
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