Metaplastic breast carcinomas are rare tumors, represent less than 1% of invasive breast cancers, and constitute a heterogeneous group of tumors defined by the World Health Organization as infiltrating ductal carcinoma but with zones of metaplastic rearrangements of Epidermoid, fusiform, chondroid, bone or mixed type. Histopathology combined with immunohistochemistry makes it possible to make the diagnosis. Treatment combines surgery, and chemotherapy, radiotherapy is discussed and hormone therapy has no place. Their prognosis is bleak and the evolution is marked by locoregional recurrences and distant metastases. We report two cases of metaplastic breast carcinoma diagnosed by histology supplemented by immunohistochemistry, the treatment consisted of a mastectomy with axillary dissection supplemented by chemotherapy.
Show abstract
Full Text
