Laboratory of Natural Substances & Synthesis and Dynamics Molecular, Moulay Ismail University Meknes, Faculty of Sciences and Technics, Errachidia, Morocco
Menthone, is a monoterpene ketone, occurs in nature and widely present in high concentration in mentha species essential oils. Also, it has become the key to the synthesis of many heterocyclic compounds exhibiting various kinds of biological activity. The objective of the present work is to synthesize new menthone derivative compounds such as menthopyrazole (HPM) and 1-phenylmenthopyrazole (PMP) by condensation of hydroxymethylenementhone with hydrazine and phenylhydrazine, respectively. The structures of these compounds were characterized by FT-IR, 1H NMR and 13C NMR spectra.
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