Volume 8, Issue 4, October 2014, Pages 1574–1580
Md. Jalal Uddin1, Md. Shamim Akhter2, Kazi Mohammed Didarul Islam3, and Md. Morsaline Billah4
1 Biotechnology and Genetic Engineering Discipline, Khulna University, Khulna-9208, Bangladesh
2 Biotechnology and Genetic Engineering Discipline, Khulna University, Khulna-9208, Bangladesh
3 Biotechnology and Genetic Engineering Discipline, Khulna University, Khulna-9208, Bangladesh
4 Biotechnology and Genetic Engineering Discipline, Khulna University, Khulna-9208, Bangladesh
Original language: English
Copyright © 2014 ISSR Journals. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
The science and practice of medicine and its primary source plays an important role in identifying the new molecule of drug through both synthetically and from that of natural origin. Most of the developing countries have adopted traditional medical practice as an integral part of their culture. Historically, all medicinal preparations were derived from plants, whether in the simple form of raw plant materials or in the refined form of crude extracts, mixtures, etc. The aim of this study was to evaluate the Cytotoxic Activity of Clerodendrum inerme (Family: Verbenaceae) and Caesalpinia crista (Family: Leguminosaceae), two widely distributed shrubs of the Sundarbans mangrove forest. A general cytotoxicity of all the extracts of C. inerme and C. crista were determined by Brine Shrimp Lethality Bioassay where the chloroformic extract of bark of C. inerme has the lowest LC50 value of 5
Author Keywords: Cytotoxic Activity, Brine Shrimp, Traditional, Sundarbans, Shrubs and Lethality.
Md. Jalal Uddin1, Md. Shamim Akhter2, Kazi Mohammed Didarul Islam3, and Md. Morsaline Billah4
1 Biotechnology and Genetic Engineering Discipline, Khulna University, Khulna-9208, Bangladesh
2 Biotechnology and Genetic Engineering Discipline, Khulna University, Khulna-9208, Bangladesh
3 Biotechnology and Genetic Engineering Discipline, Khulna University, Khulna-9208, Bangladesh
4 Biotechnology and Genetic Engineering Discipline, Khulna University, Khulna-9208, Bangladesh
Original language: English
Copyright © 2014 ISSR Journals. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
The science and practice of medicine and its primary source plays an important role in identifying the new molecule of drug through both synthetically and from that of natural origin. Most of the developing countries have adopted traditional medical practice as an integral part of their culture. Historically, all medicinal preparations were derived from plants, whether in the simple form of raw plant materials or in the refined form of crude extracts, mixtures, etc. The aim of this study was to evaluate the Cytotoxic Activity of Clerodendrum inerme (Family: Verbenaceae) and Caesalpinia crista (Family: Leguminosaceae), two widely distributed shrubs of the Sundarbans mangrove forest. A general cytotoxicity of all the extracts of C. inerme and C. crista were determined by Brine Shrimp Lethality Bioassay where the chloroformic extract of bark of C. inerme has the lowest LC50 value of 5
Author Keywords: Cytotoxic Activity, Brine Shrimp, Traditional, Sundarbans, Shrubs and Lethality.
How to Cite this Article
Md. Jalal Uddin, Md. Shamim Akhter, Kazi Mohammed Didarul Islam, and Md. Morsaline Billah, “Study on Cytotoxic Activity of Clerodendrum inerme and Caesalpinia crista by Brine Shrimp Lethality Bioassay,” International Journal of Innovation and Applied Studies, vol. 8, no. 4, pp. 1574–1580, October 2014.