[ Épidémiologie et évaluation de la sensibilité des souches d'Haemophilus influenzae isolées d’infections des voies respiratoires basses ]
Volume 20, Issue 3, June 2017, Pages 787–791
Ghita Yahyaoui1, Rajae Hendi2, and Mustapha Mahmoud3
1 Département de Microbiologie, Laboratoire Central d’Analyses Médicales, CHU Hassan II de Fès, Morocco
2 Département de Microbiologie, Laboratoire Central d’Analyses Médicales, CHU Hassan II de Fès, Morocco
3 Département de Microbiologie, Laboratoire Central d’Analyses Médicales, CHU Hassan II de Fès, Morocco
Original language: French
Copyright © 2017 ISSR Journals. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Haemophilus influenzae, holds a dominating role in the low respiratory infections. These infections constitute a real problem of public health especially because of the appearance these last years of resistant strains questioning the classic antibiotic treatment. This resistance mainly concerns betalactamins, in particular aminopenicillins. A retrospective study was made over a period of 5 years (September 2011-, 2016) with the aim of establishing the epidemiological profile of the low respiratory infections to H. influenzae, determining the resistance to antibiotics of this germ to guide better the therapeutic and preventive strategies. The identification was based on the requirements in factors X and V and the production of betalactamases was looked for by means of the cefinase. During the period of study, 123 tree strains were isolated among which 73 % resulted from intensive care units and from pneumology. The production of betalactamases for all the isolated tree strains was 31 %. Resistant strains in the amoxicillin by production of betalactamase were sensitive to the association clavulanic amoxicillin-acid in 28 % of the cases. The resistance in the other antibiotics was 16 % in the trimethoprim sulfamethoxazole, 4.8 % in fluoroquinolones and 2.5 % in tetracyclines. No resistance in cephalosporins 3rd generation was observed.
Author Keywords: Haemophilus, respiratory infections, sensibility.
Volume 20, Issue 3, June 2017, Pages 787–791
Ghita Yahyaoui1, Rajae Hendi2, and Mustapha Mahmoud3
1 Département de Microbiologie, Laboratoire Central d’Analyses Médicales, CHU Hassan II de Fès, Morocco
2 Département de Microbiologie, Laboratoire Central d’Analyses Médicales, CHU Hassan II de Fès, Morocco
3 Département de Microbiologie, Laboratoire Central d’Analyses Médicales, CHU Hassan II de Fès, Morocco
Original language: French
Copyright © 2017 ISSR Journals. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Haemophilus influenzae, holds a dominating role in the low respiratory infections. These infections constitute a real problem of public health especially because of the appearance these last years of resistant strains questioning the classic antibiotic treatment. This resistance mainly concerns betalactamins, in particular aminopenicillins. A retrospective study was made over a period of 5 years (September 2011-, 2016) with the aim of establishing the epidemiological profile of the low respiratory infections to H. influenzae, determining the resistance to antibiotics of this germ to guide better the therapeutic and preventive strategies. The identification was based on the requirements in factors X and V and the production of betalactamases was looked for by means of the cefinase. During the period of study, 123 tree strains were isolated among which 73 % resulted from intensive care units and from pneumology. The production of betalactamases for all the isolated tree strains was 31 %. Resistant strains in the amoxicillin by production of betalactamase were sensitive to the association clavulanic amoxicillin-acid in 28 % of the cases. The resistance in the other antibiotics was 16 % in the trimethoprim sulfamethoxazole, 4.8 % in fluoroquinolones and 2.5 % in tetracyclines. No resistance in cephalosporins 3rd generation was observed.
Author Keywords: Haemophilus, respiratory infections, sensibility.
Abstract: (french)
Introduction: Haemophilus influenzae, tient un rôle prépondérant dans les infections respiratoires basses. Ces infections constituent un réel problème de santé publique surtout du fait de l'apparition ces dernières années de souches résistantes remettant en cause le traitement antibiotique classique. Cette résistance intéresse essentiellement les bétalactamines notamment les aminopénicillines. Objectif de l’étude: Etablir le profil épidémiologique des infections respiratoires basses à H. influenzae, déterminer la résistance aux antibiotiques de ce germe afin de mieux guider les stratégies thérapeutiques et préventives. Matériel et méthodes: Une étude rétrospective a été effectuée sur une période de 5 ans (Septembre 2011- Septembre 2016). L'identification était basée sur les exigences en facteurs X et Vet la production de bétalactamases était recherchée à l'aide de la céfinase. Résultats: Au cours de la période d'étude, 123 souches ont été isolées dont 73% provenaient des services de réanimation et de pneumologie. La production de bétalactamases pour l'ensemble des souches isolées était de 31%. Les souches résistantes à l'amoxicilline par production de bétalactamase étaient sensibles à l'association amoxicilline-acide clavulanique dans 28% des cas. La résistance aux autres antibiotiques était de 16% au triméthoprime– sulfaméthoxazole, 4.8% aux fluoroquinolones et 2.5% aux tétracyclines. Aucune résistance aux céphalosporines 3eme génération n'a été observée.
Author Keywords: Haemophilus, infections respiratoires, sensibilité.
How to Cite this Article
Ghita Yahyaoui, Rajae Hendi, and Mustapha Mahmoud, “Epidemiology and strain sensitivity Assessment of Haemophilus influenzae isolated from low respiratory infections,” International Journal of Innovation and Applied Studies, vol. 20, no. 3, pp. 787–791, June 2017.
