Volume 26, Issue 4, July 2019, Pages 1240–1246
Essé Sonia-Estelle1, Kouamé Konan Joël2, NGuessan Anon Franck-Donald3, and Amoikon Kouakou Ernest4
1 Laboratoire de Nutrition et Pharmacologie, UFR Biosciences, Université Félix Houphouet-Boigny, BP 582 Abidjan 22, Côte d'Ivoire
2 Laboratoire de Nutrition et Pharmacologie, UFR Biosciences, Université Felix Houphouet-Boigny, BP 582 Abidjan 22, Côte d'Ivoire
3 Programme National de Nutrition (PNN), Côte d'Ivoire
4 Laboratoire de Nutrition et Pharmacologie, UFR Biosciences, Université Félix Houphouet-Boigny, BP 582 Abidjan 22, Côte d'Ivoire
Original language: French
Copyright © 2019 ISSR Journals. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
The aim of this work is to evaluate the evolution of serum metabolites and their impact during pregnancy. The methodology is based on the determination of a few serum markers in 131 women, each trimester of pregnancy. The results show that in the 2nd trimester of pregnancy, the proportion of women who have a high C-reactive protein level is higher (13.74%). The rate of women with hyperglycemia increased from 2.29% in the 1st trimester, to 6.87% in the 3rd gestational trimester. Hypercholesterolemia was observed in 4.58% of women during the first 3 months of pregnancy, 21.37% in the second trimester and 23.66% in the last gestational trimester. 8.40% of pregnant women had a triglyceride level above normal, this percentage rose to 24.43% in the 2nd quarter and reached 25.19% in the 3rd quarter. This study also showed a significant correlation between triglyceridemia in the 3rd trimester, and maternal age (p = 0.04), and between HDL-cholesterol and women's nationality. The level of education and type of latrine used by these women would be factors influencing total and LDL cholesterol levels in the 1st and 3rd gestational trimesters, respectively. Cross-analysis between C-reactive protein level and latrine type revealed an inter-relationship from the second trimester of pregnancy. In conclusion, with the exception of serum creatinine, blood glucose, cholesterol and triglyceride levels increase as pregnancy progresses among women in this study. These are therefore parameters to be controlled during the gestational period.
Author Keywords: CHU Cocody-Abidjan, socio-demographic factors, pregnant women, biochemical parameters.
Essé Sonia-Estelle1, Kouamé Konan Joël2, NGuessan Anon Franck-Donald3, and Amoikon Kouakou Ernest4
1 Laboratoire de Nutrition et Pharmacologie, UFR Biosciences, Université Félix Houphouet-Boigny, BP 582 Abidjan 22, Côte d'Ivoire
2 Laboratoire de Nutrition et Pharmacologie, UFR Biosciences, Université Felix Houphouet-Boigny, BP 582 Abidjan 22, Côte d'Ivoire
3 Programme National de Nutrition (PNN), Côte d'Ivoire
4 Laboratoire de Nutrition et Pharmacologie, UFR Biosciences, Université Félix Houphouet-Boigny, BP 582 Abidjan 22, Côte d'Ivoire
Original language: French
Copyright © 2019 ISSR Journals. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
The aim of this work is to evaluate the evolution of serum metabolites and their impact during pregnancy. The methodology is based on the determination of a few serum markers in 131 women, each trimester of pregnancy. The results show that in the 2nd trimester of pregnancy, the proportion of women who have a high C-reactive protein level is higher (13.74%). The rate of women with hyperglycemia increased from 2.29% in the 1st trimester, to 6.87% in the 3rd gestational trimester. Hypercholesterolemia was observed in 4.58% of women during the first 3 months of pregnancy, 21.37% in the second trimester and 23.66% in the last gestational trimester. 8.40% of pregnant women had a triglyceride level above normal, this percentage rose to 24.43% in the 2nd quarter and reached 25.19% in the 3rd quarter. This study also showed a significant correlation between triglyceridemia in the 3rd trimester, and maternal age (p = 0.04), and between HDL-cholesterol and women's nationality. The level of education and type of latrine used by these women would be factors influencing total and LDL cholesterol levels in the 1st and 3rd gestational trimesters, respectively. Cross-analysis between C-reactive protein level and latrine type revealed an inter-relationship from the second trimester of pregnancy. In conclusion, with the exception of serum creatinine, blood glucose, cholesterol and triglyceride levels increase as pregnancy progresses among women in this study. These are therefore parameters to be controlled during the gestational period.
Author Keywords: CHU Cocody-Abidjan, socio-demographic factors, pregnant women, biochemical parameters.
Abstract: (french)
Le but de ce travail est d’évaluer l’évolution des métabolites sériques et leur impact au cours de la grossesse. La méthodologie est basée sur le dosage de quelques marqueurs sériques chez 131 femmes, à chaque trimestre de la grossesse. Les résultats montrent qu’au 2ème trimestre de la grossesse, la proportion de femmes qui ont un taux de protéine C-réactive élevé est plus forte (13,74 %). Le taux de femmes ayant une hyperglycémie évolue de 2,29 % au 1er trimestre, à 6,87 % au 3ème trimestre gestationnel. Une hypercholestérolémie a été observée chez 4,58 % de femmes au cours des 3 premiers mois de la grossesse, 21,37 % au second trimestre et 23,66 % au dernier trimestre gestationnel. 8,40 % des femmes gestantes avaient un taux de triglycérides au-dessus de la normale, ce pourcentage s’élève à 24,43 % au 2ème trimestre et atteint 25,19 % au 3ème trimestre. Cette étude a aussi montré une interrelation significative entre la triglycéridémie au 3ème trimestre, et l’âge de la mère (p=0,04), et entre le taux de cholestérol-HDL et la nationalité des femmes. Le niveau d’instruction et le type de latrines utilisées par ces femmes seraient des facteurs influençant le taux de cholestérol total et LDL respectivement au 1er et 3ème trimestre gestationnel. L’analyse croisée entre le taux de protéine C-réactive et le type de latrines a révélé une interrelation à partir du second trimestre de la grossesse. En conclusion, à l’exception de la créatininémie, la glycémie, la cholestérolémie et la triglycéridémie augmentent au fur et à mesure que la grossesse évolue chez les femmes de cette enquête. Ce sont donc des paramètres à contrôler pendant la période gestationnelle.
Author Keywords: CHU Cocody-Abidjan, facteurs socio-démographiques, femmes gestantes, paramètres biochimiques.
How to Cite this Article
Essé Sonia-Estelle, Kouamé Konan Joël, NGuessan Anon Franck-Donald, and Amoikon Kouakou Ernest, “INTERRELATION ENTRE LES FACTEURS SOCIO-DEMOGRAPHIQUES ET LES PARAMETRES SERIQUES AU COURS DE LA GROSSESSE CHEZ DES FEMMES ENCEINTES (CHU COCODY-COTE D’IVOIRE),” International Journal of Innovation and Applied Studies, vol. 26, no. 4, pp. 1240–1246, July 2019.
