[ Efficacité d’une pommade à base de Butyrospermum parkii et d’huile de Elæis guineensis sur la croissance pilaire chez des lapins ]
Volume 31, Issue 2, December 2020, Pages 137–143
KPOROU Kouassi Elisée1, OUATTARA Sitapha2, Gouedji Yabo Parfait3, Kra Adou Mathieu4, and Djaman Allico Joseph5
1 Biochemical Pharmacodynamics laboratory, University Felix Houphouët Boigny, Côte d’Ivoire
2 Biochemical Pharmacodynamics laboratory, University Felix Houphouët Boigny, Côte d’Ivoire
3 Department of Biochemistry and Microbiology, Unité de Recherche sur les substances Naturelles bioactives, Jean Lorougnon Guede University, Daloa, Côte d'Ivoire
4 Biochemical Pharmacodynamics Laboratory, Felix Houphouët Boigny University, Abidjan, Côte d'Ivoire
5 Pharmacodynamics Biochemical Laboratory, UFR Biosciences, Felix Houphouet Boigny University, PO BOX, 582 Abidjan 22, Côte d’Ivoire
Original language: French
Copyright © 2020 ISSR Journals. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
The aim of this study was to develop an ointment of cosmetic interest in order to offer populations a hair product with local ingredients, a study of formulation and conditioning of the ointment was undertaken using oils of Elæis guineensis as active and of Butyrospermum. parkii as an excipient. These two species are known in communities for their use in hair maintenance and growth. The formulation consisted of a mixture of these two oils in precise proportions to obtain a single homogeneous phase. The ointment obtained coded PKP was applied to male and female rabbits of the species Oryctolagus cuniculus previously shaved at the rate of two applications per day for 28 days. Hair growth was measured each two days. In addition, sterility, stability and skin tolerability were assessed. The PKP ointment obtained was moderately hard, homogeneous, with a very pleasant odor and a pH of 3.93. After 28 days of experimentation, the results showed that hair growth in male rabbits was greater with a maximum cumulative length of 21 mm. The ointment did not show any microbial contamination and it remained stable over time. PKP is an ointment that would stimulate hair growth and would be a very good alternative to fight against early hair loss.
Author Keywords: Ointment, formulation, hair, vegetable oil.
Volume 31, Issue 2, December 2020, Pages 137–143
KPOROU Kouassi Elisée1, OUATTARA Sitapha2, Gouedji Yabo Parfait3, Kra Adou Mathieu4, and Djaman Allico Joseph5
1 Biochemical Pharmacodynamics laboratory, University Felix Houphouët Boigny, Côte d’Ivoire
2 Biochemical Pharmacodynamics laboratory, University Felix Houphouët Boigny, Côte d’Ivoire
3 Department of Biochemistry and Microbiology, Unité de Recherche sur les substances Naturelles bioactives, Jean Lorougnon Guede University, Daloa, Côte d'Ivoire
4 Biochemical Pharmacodynamics Laboratory, Felix Houphouët Boigny University, Abidjan, Côte d'Ivoire
5 Pharmacodynamics Biochemical Laboratory, UFR Biosciences, Felix Houphouet Boigny University, PO BOX, 582 Abidjan 22, Côte d’Ivoire
Original language: French
Copyright © 2020 ISSR Journals. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
The aim of this study was to develop an ointment of cosmetic interest in order to offer populations a hair product with local ingredients, a study of formulation and conditioning of the ointment was undertaken using oils of Elæis guineensis as active and of Butyrospermum. parkii as an excipient. These two species are known in communities for their use in hair maintenance and growth. The formulation consisted of a mixture of these two oils in precise proportions to obtain a single homogeneous phase. The ointment obtained coded PKP was applied to male and female rabbits of the species Oryctolagus cuniculus previously shaved at the rate of two applications per day for 28 days. Hair growth was measured each two days. In addition, sterility, stability and skin tolerability were assessed. The PKP ointment obtained was moderately hard, homogeneous, with a very pleasant odor and a pH of 3.93. After 28 days of experimentation, the results showed that hair growth in male rabbits was greater with a maximum cumulative length of 21 mm. The ointment did not show any microbial contamination and it remained stable over time. PKP is an ointment that would stimulate hair growth and would be a very good alternative to fight against early hair loss.
Author Keywords: Ointment, formulation, hair, vegetable oil.
Abstract: (french)
Dans le but de mettre au point une pommade d’intérêt cosmétique afin de proposer aux populations un produit capillaire avec des ingrédients locaux, une étude de formulation et de conditionnement de pommade a été entreprise à partir des huiles de Elæis guineensis comme actif et de Butyrospermum parkii comme excipient. Ces deux espèces sont connues en communautés pour leur utilisation dans l’entretien et la pousse des cheveux. La formulation a consisté en un mélange de ces deux huiles à des proportions précises pour obtenir une seule phase homogène. La pommade obtenue codée PKP a été appliquée sur les lapins mâles et femelles de l'espèce Oryctolagus cuniculus préalablement rasés en raison de deux applications par jour pendant 28 jours. La croissance pilaire a été mesurée chaque deux jours. En outre, la stérilité, la stabilité et la tolérabilité cutanée ont été évaluées. La pommade PKP obtenue est moyennement dure, homogène, avec une odeur très agréable et un pH de 3,93. Au bout des 28 jours d'expérimentation, les résultats ont montré que la croissance pilaire chez les lapins mâles a été plus importante avec une longueur cumulée maximale de 21 mm. La pommade n'a présenté aucune contamination microbienne et elle est restée stable dans le temps. PKP stimulerait la croissance pilaire et serait une très bonne alternative pour lutter contre la perte précoce des cheveux.
Author Keywords: Pommade, formulation, huile végétale.
How to Cite this Article
KPOROU Kouassi Elisée, OUATTARA Sitapha, Gouedji Yabo Parfait, Kra Adou Mathieu, and Djaman Allico Joseph, “Efficiency of an ointment based on Butyrospermum parkii and Elæis guineensis oil on rabbits hair growth,” International Journal of Innovation and Applied Studies, vol. 31, no. 2, pp. 137–143, December 2020.
