The parents of child with Cerebral Palsy through difficult periods in their lives, both in childhood of their son and in his adolescence. Adolescents with physical disabilities become more difficult to treat. This transition period often associated with disorders of behavior is an important factor in parental stress and causes deterioration in the quality of life. There are few studies that seek to assess the impact of cerebral palsy on the quality of life and mental health of parents. A study protocol consisting of questionnaires, scales and grid clinical interview were distributed and completed by 67 relatives (34 mothers and 33 fathers) of children with cerebral palsy, to measure the impact of the weakness of their children on their psychological and social well- being and their quality of life. Most of our results support our hypothesis and confirm data from the literature in this area little studied in Morocco. Indeed it seems that the suffering of parents with cerebral palsied children is more pronounced at the age of adolescence than during the phase of childhood. The impact of this pain on mothers seems more intense than on fathers. In conclusion, more having a social support and a psychological counseling, more the parent's quality of life is better.