[ Evaluation de l’activité antifongique de 4 plantes utilisées dans le traitement de Tinea capitis (la teigne) au Niger ]
Volume 42, Issue 1, March 2024, Pages 8–12
Ramatoulaye MAROU HIMA1, Alfa Keita DJIBO2, Ali Elhadji SALEY3, Souley GAMBO4, and Idrissa MOUSSA5
1 Université Abdou Moumouni de Niamey, Faculté des sciences et techniques, Niger
2 Université Abdou Moumouni de Niamey, Faculté des sciences et techniques, Niger
3 Laboratoire national de santé publique et d’expertise (LANSPEX) Niamey, Niger
4 Laboratoire national de santé publique et d’expertise (LANSPEX) Niamey, Niger
5 Université Abdou Moumouni de Niamey, Faculté des sciences et techniques, Niger
Original language: French
Copyright © 2024 ISSR Journals. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Tinea capitis is a very common fungal infection in children. It is characterized by the appearance of white circular spots on the patient’s head. Piliostigma reticulatum (D.C.) Hochst, Terminalia avicennioids (Guill and Perr), Diospyros mespiliformis Hochst and Securidaca longipedunculata Fres are plants used therapeutically in the treatment of this disease in external application, in the form of a poultice. Chemical screening of aqueous and methanolic extracts of these plants reveals the presence of phenolic and terpenoid compounds but not alkaloids. The antifungal activity of the extracts of these plants, evaluated by the agar medium diffusion method using the fungal strain Candida albicans, showed that the crude extracts of S. longepedunculata and D. mespiliform have low antifungal activity compared to Nystatin. P reticulatum and T avicennioides extracts have average antibiotic activity. The evaluation of the antifungal activity of the fractions of the methanolic extract, obtained by treatment with different solvents including hexane, dichloromethane and ethyl acetate, shows that the acetate fraction is more active than that obtained with the dichloromethane. The fractions obtained with hexane are inactive.
Author Keywords: Antifungal, ringworm, C albicans, tannin.
Volume 42, Issue 1, March 2024, Pages 8–12
Ramatoulaye MAROU HIMA1, Alfa Keita DJIBO2, Ali Elhadji SALEY3, Souley GAMBO4, and Idrissa MOUSSA5
1 Université Abdou Moumouni de Niamey, Faculté des sciences et techniques, Niger
2 Université Abdou Moumouni de Niamey, Faculté des sciences et techniques, Niger
3 Laboratoire national de santé publique et d’expertise (LANSPEX) Niamey, Niger
4 Laboratoire national de santé publique et d’expertise (LANSPEX) Niamey, Niger
5 Université Abdou Moumouni de Niamey, Faculté des sciences et techniques, Niger
Original language: French
Copyright © 2024 ISSR Journals. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Tinea capitis is a very common fungal infection in children. It is characterized by the appearance of white circular spots on the patient’s head. Piliostigma reticulatum (D.C.) Hochst, Terminalia avicennioids (Guill and Perr), Diospyros mespiliformis Hochst and Securidaca longipedunculata Fres are plants used therapeutically in the treatment of this disease in external application, in the form of a poultice. Chemical screening of aqueous and methanolic extracts of these plants reveals the presence of phenolic and terpenoid compounds but not alkaloids. The antifungal activity of the extracts of these plants, evaluated by the agar medium diffusion method using the fungal strain Candida albicans, showed that the crude extracts of S. longepedunculata and D. mespiliform have low antifungal activity compared to Nystatin. P reticulatum and T avicennioides extracts have average antibiotic activity. The evaluation of the antifungal activity of the fractions of the methanolic extract, obtained by treatment with different solvents including hexane, dichloromethane and ethyl acetate, shows that the acetate fraction is more active than that obtained with the dichloromethane. The fractions obtained with hexane are inactive.
Author Keywords: Antifungal, ringworm, C albicans, tannin.
Abstract: (french)
Tinea capitis ou teigne tondeuse est une infection fongique très fréquente chez les enfants. Elle se manifeste par l’apparition des taches circulaires blanches sur la tête du patient. Piliostigma reticulatum (D.C.) Hochst, Terminalia avicennioïdes (Guill et Perr), Diospyros mespiliformis Hochst et Securidaca longipedunculata Fres sont des plantes utilisées en thérapeutique dans le traitement de cette maladie en application externe, sous forme de cataplasme. Le screening chimique des extraits aqueux et méthanolique de ces plantes révèle la présence des composés phénoliques et terpéniques mais pas d’alcaloïdes. L’activité antifongique des extraits de ces plantes, évaluée par la méthode de diffusion en milieu gélosé en utilisant la souche fongique candida albicans, a montré que les extraits bruts de S. longepedunculata et de D. mespiliform ont une activité antifongique faible par rapport à la nystatine. Les extraits de P reticulatum et de T avicennioides présentent une activité antibiotique moyenne. L’évaluation de l’activité antifongique des fractions de l’extrait methanolique, obtenues par traitement avec différents solvants dont l’hexane, le dichlorométhane et l’acétate d’éthyle, montre que la fraction acétate est plus active que celle obtenue avec le dichloromethane. Les fractions obtenues avec l’hexane sont inactives.
Author Keywords: Antifongique, teigne, C albicans, tanin.
How to Cite this Article
Ramatoulaye MAROU HIMA, Alfa Keita DJIBO, Ali Elhadji SALEY, Souley GAMBO, and Idrissa MOUSSA, “Evaluation of the antifungal activity of 4 plants used in the treatment of Tinea capitis (ringworm) in Niger,” International Journal of Innovation and Applied Studies, vol. 42, no. 1, pp. 8–12, March 2024.
