Introduction: The World Health Organization (WHO) ranks allergies as the fourth most common chronic disease. Food allergie, defined as adverse immune reactions to food proteins, is an important public health problem that affects adults and children and may be increasing in prevalence. The aim of our study is to present the biological profile of children consulting for food allergy problems. Materials and methods: Retrospective descriptive study, spread over a period of 29 months. Concerning 177 children consulting for type I hypersensitivity problems at the CHU Ibn Rochd. Results: 109 children (61.5%) had sensitization to at least one trophallergen. It was more frequent in boys than in girls (54% vs 46%) without statistically significant difference (p= 0.27). The most frequent food allergens in our series were: sesame 21.47%, cow’s milk 20.90%, egg white 19.21%, crab 18.08%, beef 16.38%, casein 12.43%. Total IgE was ordered for 46 patients with a median of 202.3 KU, L. 30 (65%) children had elevated total IgE and 16 (35%) children had normal total IgE, with an increase in median total IgE concentration with the number of specific IgE to which a child is sensitized. Conclusion: Our study showed a high prevalence of sensitization to food allergens in children. Larger and more in-depth studies are needed to better understand the risk factors and mechanisms underlying food allergy in children in order to develop more effective and personalized prevention and treatment strategies.

Introduction: Western-blot was the first technique used to confirm the presence of anti-HIV antibodies. We aim to analyze the different profiles of the HIV western-blot (WB) test and assess their association with the different clinical and immunological stages of infection. Methods: Retrospective study included 688 cases of HIV infection confirmed by WB (HIV BLOT 2.2, MP Diagnostics), at the immunology medical analysis laboratory in collaboration with the infectious diseases department at the CHU Ibn Rochd, between January 2019 and December 2020. For the analysis of the results of the WB profiles, we adopted the interpretation criteria of the WHO (World Health Organization). Results: HIV-1 complete profile (PC: GP160, GP120, P66, P55, P51, GP41, P39, P31, P24, P17) was noted in 41.52% of cases. While 58.04% presented an incomplete HIV-1 profile. P39 was missing in 42.98% of cases, compared to 25.73% for P17, and 28.07%, 15.78%, 7.6%, 6.43%, 1.46%, %0.73% for P55, GP 51, P66, P31, GP24, GP41 respectively. A statistically significant relationship between the clinically advanced stages of HIV infection and the absence of P17, P55 and P39 antibodies in the WB test has been determined. Conclusion: WB profile during HIV infection may be useful in predicting the stages of HIV-positive patients in situations where the assay of CD4 count and viral load are not available.

Background: Hypothyroidism is among the most common endocrine disease; it is often associated with dyslipidemia which increases cardiovascular risk. This study was conducted to study the prevalence and profile of dyslipidemia during primary hypothyroidism and justify screening for dyslipidemia during hypothyroidism.Methods: Retrospective study, in the biochemistry department CHU Ibn Rochd of Casablanca from 2019 to March 2020 involving all patients who received a lipid assessment and a TSH (Thyroid Stimulating Hormone) assay in the biochemistry laboratory. TSH was estimated by an immunoenzymatic method: chemiluminescence. The LDL-assayed (Low Density Lipoprotein), HDL (High Density Lipoprotein), TG (Triglycerides), CT (Total Cholesterol) parameters were estimated by an enzymatic colorimetric method, the LDL-calculated was calculated by the friedwald formula.Results: These were 1046 patients: 66.73% Women, 33.23% Men (sex ratio M / F = 0.49). The mean age was 41.66 years ± 13.86. The mean TSH value was 23.09 mIU / L. Dyslipidemia was noted in 91.78% of cases.The prevalences of, hypoHDLemia, hypercholesterolemia, hypertriglyceridemia, hyperLDLemia, were respectively: 82.12%; 32.5%; 23.32%; 10.8%.The correlation between TSH and LDL was negative (P> 0.05) while it was positive with TG (P> 0.05), HDL (P <0.05) and CT (P> 0.05).Conclusion: Hypothyroid patients show a significant increase in serum lipids. This atherogenic lipid profile should be systematically sought when monitoring patients with hypothyroidism to prevent cardiovascular complications.