Introduction: The Katana Rural Health Zone has experienced several events including looting of health centers, the cessation of funding or the instability of nursing staff, which could have hindered the functioning of its health structures. These structures have continued to operate in this unfavorable context, thus showing themselves to be resilient. This study aims to identify the adaptive mechanisms put in place by the Katana health zone in the face of adverse events. Methodology: The study is a mixed cross-sectional study covering the period from 2014 to 2018. It is based on the identification of events that occurred in the Katana Health Zone, the analysis of the evolution of cases and deaths linked to malaria and the perceptions of key players on the nature of the events, their link with the number of cases. The study used a documentary review and individual interviews targeting 8 key players. Results: The main destabilizing events identified are related to the management of human resources, the use of health services, the breakdown of funding, the availability of curative or preventive inputs, community participation and security and safety issues. Infrastructure. The trend of the evolution of new cases with malaria is similar for all age categories. On the other hand, the evolution of deaths is different. Health services continued to provide care thanks to the coping mechanisms developed. Conclusions: The study demonstrates the precariousness of a health system heavily dependent on humanitarian aid, the interruption of which can generate dysfunction with effects on mortality, including infant mortality; the weak involvement of the government in supporting structures facing the misdeeds of disasters such as the earthquake and looting; the poverty of the population making it inaccessible to health care despite the reduction in prices and the resilience of health centers following the establishment of endogenous adaptation mechanisms..