Malnutrition is a serious Public Health problem; it is the cause of death for approximately 45% of children under the age of 5. Nutrition status assessment is one of a way which can contribute to resolve that issue. This descriptive cross sectional study has been conducted in Lwiro Health Area, in South-Kivu, at the East of DRC from December 2021 to Jun 2022. Its aim was to evaluate the nutritional status and mortality of children aged from 0-59 years. During this study, 366 children aged 0-59 months were admitted. Our data were processed and analyzed using Epi Info.; Epi Nut. Software helped us to standardize the anthropometric data. Z-score allowed us to determine the different forms of malnutrition. The chi-square test was useful to look for an association between the dependent variables and the independent and/or explicatory variables. The results showed that 62, 7% of our respondents were malnourished. The prevalence of global malnutrition was 6, 1%. Undernutrition was significant, particularly for stunting (33, 3%) and underweight (20, 8%). Our results show that 16, 7% of children had history of death under 5 years of age in their household, of which 15,5% were malnourished. Nutritional status influences the occurrence of death in children. A statically significant association was found between malnutrition and death (p=0, 0000001).