Citrus fruits and juices are an important source of bioactive compounds; called secondary metabolites, including phenolic and non-phenolic compounds. Several studies have demonstrated the antioxidant properties of these citrus fruits. Grapefruit, Citrus paradisi scientifically called is one of these citrus essentially consumed for its medical and antioxidant properties due to the presence of flavonoids, vitamin C and tannins. Characterization of two varieties of grapefruit, namely; citrus paradisi yellow and blood, was carried out through a phytochemical screening. The results obtained showed the presence of tannins, flavonoids, derivatives of anthracene, quinones, several other secondary metabolites that can be responsible for important therapeutic properties and use answered in the medical and cosmetic fields.

This work aims to investigate the influence of patients' gender on the repartition of cancer types and on death according to cancer types. It consists in a retrospective study based on 3915 cases of males and females common cancers, diagnosed and treated in Al Azhar oncology centre of Rabat between 1994 and 2004. Results showed that males display a significantly higher risk for cancer of larynx, lung and bladder, with relative risks of 5.5, 4.5 and 2.3 respectively, whereas females have a significantly higher risk for thyroid cancer, with a relative risk of 6.3, and cancers of gall bladder, liver, bone, colon-rectum, Hodgkin lymphoma, soft tissue and non Hodgkin lymphoma. As far as death is concerned, gall bladder cancer displays a death risk 4 times higher in men. Also, non Hodgkin lymphoma and larynx cancer in men are significantly associated with death, then they constitute risk factors of death in men. On the other hand, cutaneous cancers and bone cancers show higher death risk in women, with relative risks of 2.5 and 2.4 respectively. Nevertheless, we found no significant association between cancer type and death in females. In conclusion, anti-cancer strategies in Morocco and elsewhere should take into consideration the gender difference in cancer risk and death risk for common cancers, and fit their priorities to the gender of target population.

Cutaneous adverse reactions induced by drugs are common. They occur in 1 to 3% of drugs users.
The aim of this study is to determine the frequency of cutaneous adverse drug reactions, describe the clinical aspects of these reactions and determine the scores of imputability relating the possible drug-effect relationship in Morocco.
This is a prospective study of cutaneous adverse drug reactions occurring in patients in El Idrissi hospital in Kenitra during the period April 2012-April 2013. The analysis of cause-effect relationships between the drug and the occurrence of clinical and paraclinical effects is conducted by the French causality assessment method with 7 scores from 0 to 6.
Among 5137 hospital admissions, 45 patients developed 53 cutaneous adverse drug reactions, which was 1.02%. The average age of the patients was 35.39