Flooding in Senegal, particularly in cities such as Saint-Louis, has long represented a major challenge for public authorities. The Pikine neighborhood in Saint-Louis was characterized by a significant lack of sanitation infrastructure and by unplanned urban development, which hindered the proper drainage of stormwater, wastewater, and solid waste. In response to this situation, the Government of Senegal implemented a sanitation and urban restructuring project aimed at reducing flooding and its impacts in Pikine. The objective of this study was to evaluate the effectiveness of this project in terms of flood reduction as well as its economic and environmental impacts within the neighborhood. A mixed-methods approach was adopted, combining a household survey conducted with 380 heads of households and interviews with institutional stakeholders involved in the project’s implementation. The findings indicate that 88% of respondents reported no longer experiencing flooding. In addition, 52% stated that septic tanks are now emptied by vacuum trucks, while 84% confirmed that solid waste is collected by carts or trucks. Furthermore, 55% of households expressed overall satisfaction with the project. However, stakeholders emphasized the need for regular maintenance and the establishment of sustainable management mechanisms to ensure the long-term durability of the infrastructure and a lasting improvement in household living conditions.