The use of pesticides in modern agriculture is required to maintain a level of production consistent with the demand and needs. However, most of these molecules are highly toxic and hardly biodegradable. Their massive and repeated use can lead to negative consequences for all components of the environment. However, the challenge facing today is to reconcile wheat production with the international quality standards. So it is in this context that we conducted our research, consisting to identify the influence of treatment with an herbicide widely used in Morocco, on the biochemical parameters of wheat seed. To do this, we tried to make a comparative study of the physicochemical properties of five varieties of bread wheat (Triticum aestivum), and to assess their nutritional values. The results obtained show that the samples of treated wheat present highly significant different rates, higher or lower, relative to control, which can reach to: lipids (2.92