This work investigates carbon monoxide content of smoke emitted by various local and imported cigarette brands sold in Pakistani markets. Flue gas analyzer IMR 2800-p was used to analyze the smoke by using the bottle method. Nox, Sox and lower explosion limits of smoke was also obtained. The results showed clear distinction between local and imported brands as far as CO content was concerned. Almost all of the local brands exceeded the allowable limit of 20 ppm by a large margin. Cigar was also analyzed and its CO content also exceeded the allowable limit. There is a dire need to investigate these local brands by highly efficient and precise instruments to protect the masses from their harmful effects. Because Pakistan is a poor country, consumers of local brands far outnumber those of imported brands. Cigarette smoking is in itself very harmful but smoking these local brands which don't comply with International Organization for Standardization (ISO) standards for tobacco and tobacco products and regulations can only hasten the journey towards disaster.