Volume 5, Issue 1, January 2014, Pages 54–61
Raihana Nasrin Ferdousy1, Abu Md. Mamun Tarif2, Sattwikesh Paul3, Nasrin Sultana Juyena4, and Md. Mizanur Rahman5
1 Department of Surgery and Obstetrics, Bangladesh Agricultural University, Mymensingh-2202, Bangladesh
2 Department of Surgery and Obstetrics, Bangladesh Agricultural University, Mymensingh-2202, Bangladesh
3 Department of Surgery and Obstetrics, Bangladesh Agricultural University, Mymensingh-2202, Bangladesh
4 Department of Surgery and Obstetrics, Bangladesh Agricultural University, Mymensingh-2202, Bangladesh
5 Department of Surgery and Obstetrics, Bangladesh Agricultural University, Mymensingh-2202, Bangladesh
Original language: English
Copyright © 2014 ISSR Journals. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
The study was conducted to evaluate homogenous platelets rich plasma (PRP) gel in the bone healing process. There are limited researches on the use of biomaterials to assist healing process in Bangladesh done earier. Therefore, this experiment was carried out to exploit the therapeutic effects of PRP gel on healing process. For bone healing study, total 6 oblique tibial fracture cases in goats were created. Goats were divided into three groups with two animals in each group bearing weight 15-20 kg and age 1-3 years. Among these two groups were treated with homogenous PRP gel and one group was untreated served as control and fracture cases were corrected with open reduction and internal fixation using bone plate with screw and surgical stainless steel wire (18 Gauze) suture. Goats showed a satisfactory result on bone healing after using PRP gel. Post operative radiography confirmed that bone fragments were well maintained until healing occurred and radiograph showed negligible callus at 30 days, complete healing occur. On the other hands, it takes 60 days for immobilization in untreated group. In treatment groups there was no periosteal reaction at the fracture site. No postoperative complication was observed at surgical site. This study could help veterinarians to consider natural biomaterial product specially homogenous PRP gel for a good healing of bone with minimum complications. Further studies are necessary for the molecular investigation of healing process and proper establishment of commercially available of PRP gel in our country and easyiest way of application.
Author Keywords: Platelet rich plasma gel, therapeutic effect, fracture, immobilization, goat.
Raihana Nasrin Ferdousy1, Abu Md. Mamun Tarif2, Sattwikesh Paul3, Nasrin Sultana Juyena4, and Md. Mizanur Rahman5
1 Department of Surgery and Obstetrics, Bangladesh Agricultural University, Mymensingh-2202, Bangladesh
2 Department of Surgery and Obstetrics, Bangladesh Agricultural University, Mymensingh-2202, Bangladesh
3 Department of Surgery and Obstetrics, Bangladesh Agricultural University, Mymensingh-2202, Bangladesh
4 Department of Surgery and Obstetrics, Bangladesh Agricultural University, Mymensingh-2202, Bangladesh
5 Department of Surgery and Obstetrics, Bangladesh Agricultural University, Mymensingh-2202, Bangladesh
Original language: English
Copyright © 2014 ISSR Journals. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
The study was conducted to evaluate homogenous platelets rich plasma (PRP) gel in the bone healing process. There are limited researches on the use of biomaterials to assist healing process in Bangladesh done earier. Therefore, this experiment was carried out to exploit the therapeutic effects of PRP gel on healing process. For bone healing study, total 6 oblique tibial fracture cases in goats were created. Goats were divided into three groups with two animals in each group bearing weight 15-20 kg and age 1-3 years. Among these two groups were treated with homogenous PRP gel and one group was untreated served as control and fracture cases were corrected with open reduction and internal fixation using bone plate with screw and surgical stainless steel wire (18 Gauze) suture. Goats showed a satisfactory result on bone healing after using PRP gel. Post operative radiography confirmed that bone fragments were well maintained until healing occurred and radiograph showed negligible callus at 30 days, complete healing occur. On the other hands, it takes 60 days for immobilization in untreated group. In treatment groups there was no periosteal reaction at the fracture site. No postoperative complication was observed at surgical site. This study could help veterinarians to consider natural biomaterial product specially homogenous PRP gel for a good healing of bone with minimum complications. Further studies are necessary for the molecular investigation of healing process and proper establishment of commercially available of PRP gel in our country and easyiest way of application.
Author Keywords: Platelet rich plasma gel, therapeutic effect, fracture, immobilization, goat.
How to Cite this Article
Raihana Nasrin Ferdousy, Abu Md. Mamun Tarif, Sattwikesh Paul, Nasrin Sultana Juyena, and Md. Mizanur Rahman, “Role of Platelet Rich Plasma Gel in Bone Healing of Black Bengal Goats,” International Journal of Innovation and Applied Studies, vol. 5, no. 1, pp. 54–61, January 2014.
