[ Tumeur de la Granulosa de l'Ovaire ]
Volume 7, Issue 3, August 2014, Pages 1020–1024
Ikram Lazrak1, B. Laachiri2, A. Meklaa3, Jaouad Kouach4, Driss Moussaoui5, and Mohammed Dehayni6
1 Service de Gynécologie Obstétrique, Hôpital Militaire Mohamed V RABAT, Morocco
2 Service de Gynécologie Obstétrique de l'Hôpital Militaire Med V de Rabat, Morocco
3 Service de Gynécologie Obstétrique de l'Hôpital Militaire Med V de Rabat, Morocco
4 Faculté de Médecine et de Pharmacie, Université Mohamed V, Rabat, Morocco
5 Department of Gynecology-Obstetric, Military Training Hospital Med V, Faculty of Medicine and Pharmacy, Mohammed V University, Rabat, Morocco
6 Department of Gynecology-Obstetric, Military Training Hospital Med V, Faculty of Medicine and Pharmacy, Mohammed V University, Rabat, Morocco
Original language: French
Copyright © 2014 ISSR Journals. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Granulosa cell tumors of the ovary are rare, and included in the sex cord-stromal tumor category. They have a low malignancy potential and generally have a good prognosis. They are the most frequent hormone-secreting tumors of the ovary and may lead to suggestive clinical symptoms. Some biological markers (serum inhibin B and AMH) may be helpful for diagnosis, though their sensitivity is not perfect. Preoperative imaging diagnosis remains challenging due to the wide variability in morphology and lack of epidemiological data in the literature (small patient populations). From a review of the clinical of one case of granulosa cell tumor of the adult and a review of the literature, we will describe its clinical, paraclinical, therapeutic and prognostic.
Author Keywords: Ovary, Granulosa, Adult, Juvenile.
Volume 7, Issue 3, August 2014, Pages 1020–1024
Ikram Lazrak1, B. Laachiri2, A. Meklaa3, Jaouad Kouach4, Driss Moussaoui5, and Mohammed Dehayni6
1 Service de Gynécologie Obstétrique, Hôpital Militaire Mohamed V RABAT, Morocco
2 Service de Gynécologie Obstétrique de l'Hôpital Militaire Med V de Rabat, Morocco
3 Service de Gynécologie Obstétrique de l'Hôpital Militaire Med V de Rabat, Morocco
4 Faculté de Médecine et de Pharmacie, Université Mohamed V, Rabat, Morocco
5 Department of Gynecology-Obstetric, Military Training Hospital Med V, Faculty of Medicine and Pharmacy, Mohammed V University, Rabat, Morocco
6 Department of Gynecology-Obstetric, Military Training Hospital Med V, Faculty of Medicine and Pharmacy, Mohammed V University, Rabat, Morocco
Original language: French
Copyright © 2014 ISSR Journals. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Granulosa cell tumors of the ovary are rare, and included in the sex cord-stromal tumor category. They have a low malignancy potential and generally have a good prognosis. They are the most frequent hormone-secreting tumors of the ovary and may lead to suggestive clinical symptoms. Some biological markers (serum inhibin B and AMH) may be helpful for diagnosis, though their sensitivity is not perfect. Preoperative imaging diagnosis remains challenging due to the wide variability in morphology and lack of epidemiological data in the literature (small patient populations). From a review of the clinical of one case of granulosa cell tumor of the adult and a review of the literature, we will describe its clinical, paraclinical, therapeutic and prognostic.
Author Keywords: Ovary, Granulosa, Adult, Juvenile.
Abstract: (french)
Les tumeurs de la granulosa sont des tumeurs ovariennes rares, appartenant à la famille des tumeurs du stroma et des cordons sexuels. Elles ont un faible degré de malignité et sont de bon pronostic. Elles constituent la première cause de tumeur ovarienne hormonosécrétante à l'origine d'une symptomatologie clinique parfois évocatrice. Certains marqueurs biologiques (inhibine B et AMH) peuvent être informatifs pour le diagnostic mais ils ont une sensibilité encore imparfaite. Le diagnostic préopératoire en imagerie est un challenge, compte tenu de leur grande variabilité morphologique et du manque de données épidémiologiques et séméiologiques dans la littérature (populations de petite taille). À travers une observation clinique de tumeur de la granulosa de type adulte assortie d'une revue de la littérature, nous définirons ses particularités cliniques, paracliniques, thérapeutiques et pronostiques.
Author Keywords: Ovaire, Granulosa, Adulte, Juvénile.
How to Cite this Article
Ikram Lazrak, B. Laachiri, A. Meklaa, Jaouad Kouach, Driss Moussaoui, and Mohammed Dehayni, “Granulosa-cell tumor of the ovary,” International Journal of Innovation and Applied Studies, vol. 7, no. 3, pp. 1020–1024, August 2014.
