[ Exploration des causes de perturbation des transaminases chez les personnes vivant avec le VIH-SIDA (PVVIH) de l’hôpital général de référence (HGR) de la FOMULAC-KATANA en RD Congo ]
Volume 23, Issue 2, May 2018, Pages 211–216
F. Muhimuzi Namuzirhu1, B. Kalimira Kachelewa2, R. Tsongo kyatsandire3, R. Mwambusa Bacikenge4, and S. Cikubirha Rugamika5
1 Institut Supérieur des Techniques Médicales de Nyangezi, RD Congo
2 Institut Supérieur des Techniques Médicales de Kirotshe, RD Congo
3 Institut Supérieur des Techniques Médicales de Kirotshe, RD Congo
4 Institut Supérieur des Techniques Médicales de Nyangezi, RD Congo
5 Institut Supérieur des Techniques Médicales de Nyangezi, RD Congo
Original language: French
Copyright © 2018 ISSR Journals. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Objective: To identify the factors of risk that are in link with the disruption of the hepatic enzymes (GOT and GPT) at the PVVIH of the HGR FOMULAC Katana. Materials and methods: A transverse survey to analytic aim has been led on 150 PVVIH having frequented the HGR FOMULAC Katana during the active period of May 1st, 2011 to May 1st 2012. The data in relation with the biologic state of the PVVIH and the reasons of the disruptions of the transaminases have been collected and have been analyzed by means of software Epi Info version 3.5.1. The percentage, the average with deviation standard (DS) has been found and the doorstep of significance has been fixed to a p value < 0, 05. Results: The GOT transaminases and GPT were disrupted respectively to a rate of 14% and 11% at the aged PVVIH, of feminine sex, co infected by the viruses of B hepatitis and C, under ARV consuming the alcohol. Conclusion: The transaminases were disrupted at the PVVIH followed to the HGR katana. A good hold in load, the non-Consumption of alcohol and a regular control of the biologic parameters as the dosages of the hepatic enzymes, the serodiagnosis of B hepatitis and C could reduce the effects hepatotoxic by our PVVIH.
Author Keywords: transaminases, HIV-AIDS, PVVIH, DR Congo.
Volume 23, Issue 2, May 2018, Pages 211–216
F. Muhimuzi Namuzirhu1, B. Kalimira Kachelewa2, R. Tsongo kyatsandire3, R. Mwambusa Bacikenge4, and S. Cikubirha Rugamika5
1 Institut Supérieur des Techniques Médicales de Nyangezi, RD Congo
2 Institut Supérieur des Techniques Médicales de Kirotshe, RD Congo
3 Institut Supérieur des Techniques Médicales de Kirotshe, RD Congo
4 Institut Supérieur des Techniques Médicales de Nyangezi, RD Congo
5 Institut Supérieur des Techniques Médicales de Nyangezi, RD Congo
Original language: French
Copyright © 2018 ISSR Journals. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Objective: To identify the factors of risk that are in link with the disruption of the hepatic enzymes (GOT and GPT) at the PVVIH of the HGR FOMULAC Katana. Materials and methods: A transverse survey to analytic aim has been led on 150 PVVIH having frequented the HGR FOMULAC Katana during the active period of May 1st, 2011 to May 1st 2012. The data in relation with the biologic state of the PVVIH and the reasons of the disruptions of the transaminases have been collected and have been analyzed by means of software Epi Info version 3.5.1. The percentage, the average with deviation standard (DS) has been found and the doorstep of significance has been fixed to a p value < 0, 05. Results: The GOT transaminases and GPT were disrupted respectively to a rate of 14% and 11% at the aged PVVIH, of feminine sex, co infected by the viruses of B hepatitis and C, under ARV consuming the alcohol. Conclusion: The transaminases were disrupted at the PVVIH followed to the HGR katana. A good hold in load, the non-Consumption of alcohol and a regular control of the biologic parameters as the dosages of the hepatic enzymes, the serodiagnosis of B hepatitis and C could reduce the effects hepatotoxic by our PVVIH.
Author Keywords: transaminases, HIV-AIDS, PVVIH, DR Congo.
Abstract: (french)
Objectif: Identifier les facteurs de risque qui sont en liaison avec la perturbation des enzymes hépatiques (GOT et GPT) chez les PVVIH de l’HGR FOMULAC Katana. Matériels et méthodes: Une étude transversale à visée analytique a été menée sur 85 PVVIH ayant fréquentées l’HGR FOMULAC Katana pendant la période allant du 1er Mai 2011 au 1er Mai 2012. Les données en rapport avec l’état biologique des PVVIH et les causes des perturbations des transaminases ont été collectées et analysées au moyen de logiciel Epi Info version 3.5.1. Le pourcentage, la moyenne avec déviation standard(DS) ont été trouvé et le seuil de signification a été fixé à une valeur p < 0,05. Résultats: Les transaminases GOT et GPT étaient perturbés respectivement à un taux de 14% et 11% chez les PVVIH âgées, de sexe féminin, co-infectées par les virus des hépatites B et C, sous ARV consommant l’alcool. Conclusion: Les transaminases étaient perturbées chez les PVVIH suivie à l’HGR katana. Une bonne prise en charge, la Non-consommation d’alcool et un contrôle régulier des paramètres biologiques tels que les dosages des enzymes hépatiques, le sérodiagnostic des hépatites B et C pourraient réduire les effets hépatotoxiques auprès de nos PVVIH.
Author Keywords: transaminases, facteurs associés, PVVIH, HGR FOMULAC Katana.
How to Cite this Article
F. Muhimuzi Namuzirhu, B. Kalimira Kachelewa, R. Tsongo kyatsandire, R. Mwambusa Bacikenge, and S. Cikubirha Rugamika, “Exploration of the reasons of disruption of the transaminases at people living with the HIV-AIDS (PVVIH) of the general hospital of reference (HGR) of the FOMULAC-KATANA in DR Congo,” International Journal of Innovation and Applied Studies, vol. 23, no. 2, pp. 211–216, May 2018.
