Volume 39, Issue 3, May 2023, Pages 1220–1222
Naoual Hasnaoui1, Rachid Taoufiq2, and Mariem Karhate Andaloussi3
1 Department of Clinical Hematology, Hassan II Oncology Centre, Oujda, Morocco
2 Department of Thoracic Surgery, Al Farabi Regional Hospital, Oujda, Morocco
3 Department Pneumology, Al Farabi Regional Hospital, Oujda, Morocco
Original language: English
Copyright © 2023 ISSR Journals. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Introduction: POEMS syndrome consisting of polyneuropathy (P), organomegaly (O), endocrinopathy (E), monoclonal gammopathy (M) and skin changes (S), is a rare paraneoplastic syndrome resulting from an underlying plasma cell disorder. The multi-organ involvement associated with this syndrome extends beyond those listed in the acronym, such as extravascular volume overload (pleural effusion, ascites, oedema), sclerotic bone lesions, papilledema and thrombocytosis, and not all of the features listed in the acronym are required for diagnosis. Observation: we report a rare case of POEMS syndrome in an 83-year-old man with bilateral pleural effusions, initially attributed to pleural tuberculosis given the endemic context. Conclusion: the pleural involvement in patients with POEMS in our endemic tuberculosis context makes diagnosis difficult, delaying treatment. However, a good history and physical examination followed by appropriate investigations can differentiate this syndrome from other diseases.
Author Keywords: POEMS Syndrome, pleural effusion, tuberculosis, Morocco.
Naoual Hasnaoui1, Rachid Taoufiq2, and Mariem Karhate Andaloussi3
1 Department of Clinical Hematology, Hassan II Oncology Centre, Oujda, Morocco
2 Department of Thoracic Surgery, Al Farabi Regional Hospital, Oujda, Morocco
3 Department Pneumology, Al Farabi Regional Hospital, Oujda, Morocco
Original language: English
Copyright © 2023 ISSR Journals. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Introduction: POEMS syndrome consisting of polyneuropathy (P), organomegaly (O), endocrinopathy (E), monoclonal gammopathy (M) and skin changes (S), is a rare paraneoplastic syndrome resulting from an underlying plasma cell disorder. The multi-organ involvement associated with this syndrome extends beyond those listed in the acronym, such as extravascular volume overload (pleural effusion, ascites, oedema), sclerotic bone lesions, papilledema and thrombocytosis, and not all of the features listed in the acronym are required for diagnosis. Observation: we report a rare case of POEMS syndrome in an 83-year-old man with bilateral pleural effusions, initially attributed to pleural tuberculosis given the endemic context. Conclusion: the pleural involvement in patients with POEMS in our endemic tuberculosis context makes diagnosis difficult, delaying treatment. However, a good history and physical examination followed by appropriate investigations can differentiate this syndrome from other diseases.
Author Keywords: POEMS Syndrome, pleural effusion, tuberculosis, Morocco.
How to Cite this Article
Naoual Hasnaoui, Rachid Taoufiq, and Mariem Karhate Andaloussi, “Pleural effusion revealing a rare haematological disease,” International Journal of Innovation and Applied Studies, vol. 39, no. 3, pp. 1220–1222, May 2023.
