Volume 41, Issue 2, December 2023, Pages 481–488
Virginie Atto1, Kamo Irie Lou Emilie2, Adepo Yapo Prospère3, and Nene Bi Semi Anthèlmel4
1 Laboratoire de Physiologie, Pharmacologie, Unité de Formation et de Recherche Biosciences, Université Félix HOUPHOUËT-BOIGNY, Côte d’Ivoire
2 Pasteur Institute, Abidjan, Côte d’Ivoire
3 Laboratory of Biotechnology, Agriculture and Development of Biological Resources, Biosciences, Training and Research Unit, Félix Houphouët-Boigny University, 22 BP 582 Abidjan, Côte d’Ivoire
4 Laboratory of Biology and Health, Biosciences, Training and Research Unit, Félix Houphouët-Boigny University, 22 BP 582 Abidjan 22, Côte d’Ivoire
Original language: English
Copyright © 2023 ISSR Journals. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Petrosolinum crispum (Apiaceae) is a plant commonly used in traditional African medicine for improving the health of populations including wound care; the aim of this study was to evaluate the healing properties of Petrosolinum crispum (Apiaceae) leaves on second degree incision wounds in Wistar rats. This study was carried out on 28 rats divided into 7 batches of 4 rats, one of which was an untreated control and the other 6 received daily applications of test substances. The results showed that the wounds treated with 500 mg/ml of the aqueous extract of leaves of Petrosolinum crispum (EAPc) healed first. At this concentration, the healing time is the same as that of rats treated with Flammazine, 16 days against. For the batches treated with Betadine and EAPc at 1000 mg/ml, the wounds had completely healed in 26 days. However, those of the untreated rats had healed 95% by the 28th day. This effect of the extract is due to the bioactive substances present within the plant. These results therefore suggest that this extract has healing activity.
Author Keywords: Petrosolinum crispum, incision wounds, cicatrization, rats.
Virginie Atto1, Kamo Irie Lou Emilie2, Adepo Yapo Prospère3, and Nene Bi Semi Anthèlmel4
1 Laboratoire de Physiologie, Pharmacologie, Unité de Formation et de Recherche Biosciences, Université Félix HOUPHOUËT-BOIGNY, Côte d’Ivoire
2 Pasteur Institute, Abidjan, Côte d’Ivoire
3 Laboratory of Biotechnology, Agriculture and Development of Biological Resources, Biosciences, Training and Research Unit, Félix Houphouët-Boigny University, 22 BP 582 Abidjan, Côte d’Ivoire
4 Laboratory of Biology and Health, Biosciences, Training and Research Unit, Félix Houphouët-Boigny University, 22 BP 582 Abidjan 22, Côte d’Ivoire
Original language: English
Copyright © 2023 ISSR Journals. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Petrosolinum crispum (Apiaceae) is a plant commonly used in traditional African medicine for improving the health of populations including wound care; the aim of this study was to evaluate the healing properties of Petrosolinum crispum (Apiaceae) leaves on second degree incision wounds in Wistar rats. This study was carried out on 28 rats divided into 7 batches of 4 rats, one of which was an untreated control and the other 6 received daily applications of test substances. The results showed that the wounds treated with 500 mg/ml of the aqueous extract of leaves of Petrosolinum crispum (EAPc) healed first. At this concentration, the healing time is the same as that of rats treated with Flammazine, 16 days against. For the batches treated with Betadine and EAPc at 1000 mg/ml, the wounds had completely healed in 26 days. However, those of the untreated rats had healed 95% by the 28th day. This effect of the extract is due to the bioactive substances present within the plant. These results therefore suggest that this extract has healing activity.
Author Keywords: Petrosolinum crispum, incision wounds, cicatrization, rats.
How to Cite this Article
Virginie Atto, Kamo Irie Lou Emilie, Adepo Yapo Prospère, and Nene Bi Semi Anthèlmel, “Healing effects of aqueous extract of leaves of Petrosolinum crispum (Apiaceae) on induce wounds in rats,” International Journal of Innovation and Applied Studies, vol. 41, no. 2, pp. 481–488, December 2023.
