Volume 7, Issue 1, July 2014, Pages 58–64
Sabaa Tahier Mohammed1, Sahar A. H. AL-Sharqi2, and Nidaa Mohammed3
1 Department of Biology, College of Science, AL-Mustansiriya University, Baghdad, Iraq
2 Department of Biology, College of Science, AL-Mustansiriya University, Baghdad, Iraq
3 Department of Biology, College of Science, AL-Mustansiriya University, Baghdad, Iraq
Original language: English
Copyright © 2014 ISSR Journals. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
The principal objective for our study was to evaluate the efficacy of Carica papaya seeds against Entamoeba histolytica infection compared with metronidazole by using mice models. A single oral dose of Caricapapaya seeds water extracts of up to (0.1ml ?mice?day) reduced parasite appearance in feces and disappear completely atthe 8th day compared with metronidazole the cysts parasite continued till 10th day. The histomorphological study findings showed in the group which was given Carica papaya seeds the majority of tissue intestine return to normalshape. These finding indicated that Carica papaya seeds may be effective in treating Entamoeba histolytica.
Author Keywords: Entamoeba histolytica, Carica papaya, seeds water extract, metronidazole, intestinal tissue.
Sabaa Tahier Mohammed1, Sahar A. H. AL-Sharqi2, and Nidaa Mohammed3
1 Department of Biology, College of Science, AL-Mustansiriya University, Baghdad, Iraq
2 Department of Biology, College of Science, AL-Mustansiriya University, Baghdad, Iraq
3 Department of Biology, College of Science, AL-Mustansiriya University, Baghdad, Iraq
Original language: English
Copyright © 2014 ISSR Journals. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
The principal objective for our study was to evaluate the efficacy of Carica papaya seeds against Entamoeba histolytica infection compared with metronidazole by using mice models. A single oral dose of Caricapapaya seeds water extracts of up to (0.1ml ?mice?day) reduced parasite appearance in feces and disappear completely atthe 8th day compared with metronidazole the cysts parasite continued till 10th day. The histomorphological study findings showed in the group which was given Carica papaya seeds the majority of tissue intestine return to normalshape. These finding indicated that Carica papaya seeds may be effective in treating Entamoeba histolytica.
Author Keywords: Entamoeba histolytica, Carica papaya, seeds water extract, metronidazole, intestinal tissue.
How to Cite this Article
Sabaa Tahier Mohammed, Sahar A. H. AL-Sharqi, and Nidaa Mohammed, “Antiparasitic activity of Natural Plant Carica papaya Seed Extract against Gastrointestinal Parasite Entamoeba histolytica,” International Journal of Innovation and Applied Studies, vol. 7, no. 1, pp. 58–64, July 2014.
